3978-87-8 Usage
Description
N-Benzyl-3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-Methylpropan-1-aMine is a complex organic compound with a specific molecular structure that plays a significant role in the pharmaceutical industry. It is characterized by its unique arrangement of benzyl, dihydro-dibenzoazepinyl, and methylpropanamine groups, which contribute to its chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
N-Benzyl-3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-Methylpropan-1-aMine is used as a reactant in the preparation of hydroxy metabolites of tricyclic antidepressants. Its involvement in the synthesis process is crucial for the development of these medications, which are widely prescribed for the treatment of various mental health disorders, including depression and anxiety.
N-Benzyl-3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-Methylpropan-1-aMine's specific structure allows it to participate in chemical reactions that lead to the formation of hydroxy metabolites, which are essential for the therapeutic effects of tricyclic antidepressants. By acting as a reactant, N-Benzyl-3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-Methylpropan-1-aMine contributes to the overall efficacy and safety of these medications, making it an important component in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 3978-87-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,7 and 8 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3978-87:
(6*3)+(5*9)+(4*7)+(3*8)+(2*8)+(1*7)=138
138 % 10 = 8
So 3978-87-8 is a valid CAS Registry Number.
3978-87-8Relevant articles and documents
Manganese-Catalyzed Anti-Markovnikov Hydroamination of Allyl Alcohols via Hydrogen-Borrowing Catalysis
Das, Kuhali,Sarkar, Koushik,Maji, Biplab
, p. 7060 - 7069 (2021/06/30)
Controlling the selectivity in a hydroamination reaction is an extremely challenging yet highly desirable task for the diversification of amines. In this article, a selective formal anti-Markovnikov hydroamination of allyl alcohols is presented. It enables the versatile synthesis of valuable γ-amino alcohol building blocks. A phosphine-free Earth's abundant manganese(I) complex catalyzed the reaction under hydrogen-borrowing conditions. A vast range of aliphatic, aromatic amines, drug molecules, and natural product derivatives underwent successful hydroamination with primary and secondary allylic alcohols with excellent functional group tolerance (57 examples). The catalysis could be performed on a gram scale and has been applied for the synthesis of drug molecules. The mechanistic studies revealed the metal-ligand bifunctionality as well as hemilability of the ligand backbone as the key design principle for the success of this catalysis.
