41267-62-3Relevant articles and documents
Alternative strategies for the stereoselective synthesis of enantioenriched 6-arylated piperidin-2-ones
Sallio, Romain,Lebrun, Stephane,Agbossou-Niedercorn, Francine,Michon, Christophe,Deniau, Eric
, p. 998 - 1004 (2012/09/22)
Two alternative synthetic approaches to a variety of enantioenriched 6-arylated piperidin-2-ones have been developed. The first one is based on the hydrogenation of suitably arylated chiral cyclic enehydrazides. The second approach relies on the asymmetric catalytic hydrogenation of the corresponding N-alkylated precursors. 2012 Elsevier Ltd.