4264-29-3 Usage
Description
(E)-2-Nitrostilbene, also known as 1-nitro-2-(E-phenylethenyl) benzene, is a chemical compound with the molecular formula C14H11NO2. It is a yellow crystalline solid that possesses distinctive chemical and physical properties due to the presence of a nitro group (-NO2). (E)-2-Nitrostilbene is recognized for its potential applications in various fields, including pharmaceuticals, dyes, and perfumes, as well as its use as a key intermediate in organic synthesis. Furthermore, (E)-2-Nitrostilbene has garnered interest for its potential antimicrobial and antitumor properties, which makes it a promising candidate for further pharmacological research.
Uses
Used in Pharmaceutical Industry:
(E)-2-Nitrostilbene is used as a key intermediate for the production of various pharmaceuticals. Its unique chemical structure allows it to be a valuable component in the synthesis of different medicinal compounds, contributing to the development of novel drugs and therapies.
Used in Dye Industry:
In the dye industry, (E)-2-Nitrostilbene is utilized as a starting material for the synthesis of various dyes. Its yellow crystalline nature and chemical properties make it suitable for creating a range of colorants used in different applications, such as textiles, plastics, and printing inks.
Used in Perfume Industry:
(E)-2-Nitrostilbene is also used as a component in the perfume industry, where its distinctive chemical properties contribute to the creation of unique and complex fragrances. Its ability to be a part of organic synthesis allows for the development of novel scent compounds that can be used in various perfume formulations.
Used in Organic Synthesis:
(E)-2-Nitrostilbene serves as a crucial intermediate in organic synthesis, enabling the preparation of a wide array of organic compounds. Its reactivity and potential applications make it a valuable chemical in both industrial and academic settings, facilitating the development of new materials and compounds with diverse uses.
Used in Antimicrobial Applications:
(E)-2-Nitrostilbene has been studied for its potential antimicrobial properties, making it an interesting target for further research in the development of new antimicrobial agents. Its ability to inhibit the growth of certain microorganisms could lead to the creation of novel treatments and preventive measures against various infections.
Used in Antitumor Research:
The antitumor potential of (E)-2-Nitrostilbene has also been a subject of interest, with its possible application in the development of new cancer therapies. Further pharmacological research could reveal its effectiveness in targeting specific cancer cells and contribute to the advancement of cancer treatment options.
Check Digit Verification of cas no
The CAS Registry Mumber 4264-29-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,6 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4264-29:
(6*4)+(5*2)+(4*6)+(3*4)+(2*2)+(1*9)=83
83 % 10 = 3
So 4264-29-3 is a valid CAS Registry Number.
4264-29-3Relevant articles and documents
Wittig Olefination Using Phosphonium Ion-Pair Reagents Incorporating an Endogenous Base
Vetter, Anna C.,Gilheany, Declan G.,Nikitin, Kirill
, p. 1457 - 1462 (2021/03/08)
Despite common perception, the use of strong bases in Wittig chemistry is utterly unnecessary: we report a series of novel ion-pair phosphonium carboxylate reagents which are essentially "storable ylides". These reagents are straightforwardly prepared in excellent yields, and their fluxional nature permits clean olefination of a broad range of aldehydes and even hemiacetals.
Palladium Complexes with Phenoxy- And Amidate-Functionalized N-Heterocyclic Carbene Ligands Based on 3-Phenylimidazo[1,5- a]pyridine: Synthesis and Catalytic Application in Mizoroki-Heck Coupling Reactions with Ortho-Substituted Aryl Chlorides
Hung, Cheng-Hau,Zheng, Wei-Yuan,Lee, Hon Man
, p. 702 - 713 (2021/04/02)
Mononuclear and tetranuclear palladium complexes with functionalized "abnormal"N-heterocyclic carbene (aNHC) ligands based on 3-phenylimidazo[1,5-a]pyridine were synthesized. All of the new complexes were structurally characterized by single-crystal X-ray diffraction studies. The new complexes were applied in the Mizoroki-Heck coupling reaction of aryl chlorides with alkenes in neat n-tetrabutylammonium bromide (TBAB). The mononuclear palladium complex with a tridentate phenoxy- and amidate-functionalized aNHC ligand displayed activity superior to that of the palladium complex with a bidentate amidate-functionalized aNHC ligand. The new tetranuclear complex with the tridentate ligand displayed the best activities, capable of the activation of deactivated aryl chlorides as substrates with a low Pd atom loading. Even challenging sterically demanding ortho-substituted aryl chlorides were successfully utilized as substrates. The studies revealed that the robustness of the catalyst precursor is crucial in delivering high catalytic activities. Also, the promising use of tetranuclear palladium complexes with functionalized aNHC ligands as the catalyst precursors in the Mizoroki-Heck coupling reaction in neat TBAB was demonstrated.
Pd-Catalyzed Reductive Cyclization of Nitroarenes with CO2 as the CO Source
Guan, Xinyu,Zhu, Haoran,Zhao, Yingwei,Driver, Tom G.
supporting information, p. 57 - 60 (2019/12/11)
A reductive amination process that constructs indoles, carbazoles or benzimidazoles from nitroarenes – irrespective of their electronic or steric nature – was developed that uses CO2 as the source of CO. The process is robust, tolerating common gaseous components of flue gas (H2S, SO2, NO and H2O) without adversely affecting the reductive cyclization.
