4442-83-5

Basic information

• Product Name: Benzeneethanol, b-cyclohexyl-
• CAS NO: 4442-83-5
• Molecular Formula: C14H20O
• Molecular Weight: 204.312
• Mol File: 4442-83-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, b-cyclohexyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, b-cyclohexyl-(4442-83-5)
• EPA Substance Registry System: Benzeneethanol, b-cyclohexyl-(4442-83-5)

Safety Data

• Hazardous Substances Data: 4442-83-5(Hazardous Substances Data)

Upstream product

• 144313-98-4 2-cyclohexyl-2-phenyloxirane 
• 108-86-1 bromobenzene 
• 695-12-5 vinylcyclohexane 
• 5700-44-7 1-phenyl-1-cyclohexylethylene 
• 32231-03-1 (1-phenyl-cyclohexyl)-acetic acid 
• 140-29-4 phenylacetonitrile 
• 3893-23-0 cyclohexyl phenyl acetonitrile 
• 542-18-7 cyclohexyl chloride 
• 100-42-5 styrene 
• 953-91-3 cyclohexyl tosylate 
• 13027-73-1 methyl 2-cyclohexyl-2-phenylacetate 
• 117-34-0 2,2-diphenylacetic acid 
• 82517-30-4 cyclohexyl(phenyl)diazomethane 
• 3894-09-5 2-cyclohexyl-2-phenylacetic acid 

Downstream Products

• 152681-78-2 diethyl (2-cyclohexyl-2-phenylethyl)malonate 
• 152643-45-3 2-cyclohexyl-2-phenyl-1-iodoethane 
• 101276-96-4 3-cyclohexyl-3-phenylbutanoic acid 
• 108773-91-7 4-cyclohexyl-1,2,3,4-tetrahydronaphth-1-one 
• 5664-22-2 (+/-)-2-cyclohexyl-2-phenylacetaldehyde 
• 61636-63-3 2-Cyclohexyl-2-phenylethyl-p-toluolsulfonat 

Relevant articles and documents

Regiodivergent Hydroborative Ring Opening of Epoxides via Selective C-O Bond Activation

A magnesium-catalyzed regiodivergent C-O bond cleavage protocol is presented. Readily available magnesium catalysts achieve the selective hydroboration of a wide range of epoxides and oxetanes yielding secondary and tertiary alcohols in excellent yields and regioselectivities. Experimental mechanistic investigations and DFT calculations provide insight into the unexpected regiodivergence and explain the different mechanisms of the C-O bond activation and product formation.

Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins

Considering that stoichiometric borane and oxidant are required in the classical alkene anti-Markovnikov hydration process, it remains appealing to achieve the transformation in a catalytic protocol. Herein, a visible-light-mediated anti-Markovnikov addition of water to alkenes by using an organic photoredox catalyst in conjunction with a redox-active hydrogen atom donor was developed, which avoided the need for a transition-metal catalyst, stoichiometric borane, as well as oxidant. Both terminal and internal olefins are readily accommodated in this transformation to obtain corresponding primary and secondary alcohols in good yields with single regioselectivity. This procedure can be scaled up to gram scale with a 230 turnover number based on photocatalyst.

Remarkable Change of the Diastereoselection in the Dye-Sensitized Ene Hydroperoxidation of Chiral Alkenes by Zeolite Confinement

(Equation presented) The ene reaction of singlet oxygen with chiral trisubstituted alkenes bearing an alkyl and a phenyl group at the stereogenic center is erythro diastereoselective in solution and threo diastereoselective if carried out within zeolite Na-Y. The change of the diastereoselection trend by zeolite confinement is attributed to a synergism of steric effects and cation-π interactions.