4589-12-2

Basic information

• Product Name: N-(pyridin-2-yl)benzamide
• Synonyms: benzamide, N-2-pyridinyl-; N-(Pyridin-2-yl)benzamide
• CAS NO: 4589-12-2
• Molecular Formula: C₁₂H₁₀N₂O
• Molecular Weight: 198.2206
• Mol File: 4589-12-2.mol
• Article Data: 121

Chemical Properties

• Boiling Point: 265.8°C at 760 mmHg
• Flash Point: 114.5°C
• Density: 1.227g/cm³
• Vapor Pressure: 0.00898mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: N-(pyridin-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(pyridin-2-yl)benzamide(4589-12-2)
• EPA Substance Registry System: N-(pyridin-2-yl)benzamide(4589-12-2)

Safety Data

• Hazardous Substances Data: 4589-12-2(Hazardous Substances Data)

Usage

General Description

N-(pyridin-2-yl)benzamide is a chemical compound with the molecular formula C14H11N3O. It is an aromatic amide derivative with a benzene ring attached to a pyridine ring and a carbonyl group. N-(pyridin-2-yl)benzamide is commonly used as an intermediate for the synthesis of various pharmaceutical and agrochemical products. It has also been studied for its potential biological activities, including its ability to inhibit certain enzymes and receptors. N-(pyridin-2-yl)benzamide is a yellow solid at room temperature and is sparingly soluble in water, but soluble in organic solvents. Its properties and uses make it an important compound in the fields of medicinal chemistry and chemical synthesis.

Upstream product

• 504-29-0 2-aminopyridine 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 718-33-2 di-[2]pyridyl-carbodiimide 
• 71653-61-7 N-benzoyl-N-(pyridin-2-yl)benzamide 
• 7504-87-2 N,N'-dibenzoylimido-1,2-dihydropyridine 
• 82093-41-2 (Z)-N-(pyridin-2-yl)benzimidoyl cyanide 
• 106-49-0 p-toluidine 
• 82776-72-5 N-(Pyridine-2-carbonyl)-N-pyridin-2-yl-benzamide 
• 82776-76-9 N-Pyridin-2-yl-N-(4-pyrrolidin-1-yl-pyridine-2-carbonyl)-benzamide 
• 590-28-3 potassium cyanate 
• 107264-09-5 1-fluoro-pyridinium tetrafluoroborate 
• 100-47-0 benzonitrile 
• 82776-74-7 N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-pyridin-2-yl-benzamide 

Downstream Products

• 27060-34-0 N-(pyridin-2-yl)benzenecarbothioamide 
• 14178-42-8 2-benzamidopyridine 1-oxide 
• 5454-05-7 1-(2'-pyridyl)-5-phenyltetrazole 
• 78455-28-4 N-(2'-pyridyl)benzimidoyl chloride 
• 82093-44-5 N-(2-pyridyl)benzimidoyl chloride hydrochloride 
• 1009-14-9 phenyl butyl ketone 
• 938-87-4 2-methyl-1-phenyl-butan-1-one 
• 82776-72-5 N-(Pyridine-2-carbonyl)-N-pyridin-2-yl-benzamide 
• 82776-76-9 N-Pyridin-2-yl-N-(4-pyrrolidin-1-yl-pyridine-2-carbonyl)-benzamide 
• 82776-74-7 N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-pyridin-2-yl-benzamide 
• 779-24-8 2-phenyl[1,2,4]triazolo[1,5-a]pyridine 

Relevant articles and documents

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Single-pot tandem oxidative/C-H modification amidation process using ultrasmall PdNP-encapsulated porous organosilica nanotubes

Herein, we studied a single-pot method with a dual catalysis process towards the conversion of primary aromatic alcohols to amides using ultrasmall PdNPs of controlled uniform size (1.8 nm) inside hybrid mesoporous organosilica nanotubes (MO-NTs). The cat

Metal-free oxidative decarbonylative halogenation of fused imidazoles

An efficient strategy has been developed for the deformylative halogenation of carbaldehyde imidazo-fused heterocycles in the presence of TBHP controlled by temperature. A convenient and sequential functionalization (C8 to C3) portrays the synthetic utility of the current method.N-Heterocycle benzamide products were also observedviathe ring opening of imidazopyridines through the cleavage of C-C bond at high temperatures. Features of this method include temperature-controlled excellent regioselectivity, mild conditions and functional group tolerance.

Method for preparing amide compound by photocatalysis of nitrogen-containing heterocyclic compound

The invention provides a method for preparing an amide compound by photocatalysis of a nitrogen-containing heterocyclic compound. The method comprises the following steps: mixing the nitrogen-containing heterocyclic compound, organic carboxylic acid and tetrahalomethane in a solvent, adding a catalyst, and reacting under the illumination condition to prepare the amide compound. According to the invention, the organic carboxylic acid, the nitrogen-containing heterocyclic compound containing reactive hydrogen on nitrogen atoms and the tetrahalomethane are used as raw materials, so the raw materials are wide in source, low in cost and high in safety, and large-scale production is facilitated; the halogen simple substance is co-produced in the reaction process, the added value is high, a large amount of waste is prevented from being generated, and the method has high atom economy and environmental friendliness; light conditions are adopted to replace traditional heating and high-pressure conditions, the reaction conditions are mild, environmental pollution is reduced, and the reaction cost is reduced; the method has the advantages of good substrate applicability, mild process conditions, environmental protection, simple process, simple and feasible operation method, and facilitation of popularization and application.