471903-20-5

Basic information

• Product Name: 4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexanone
• Synonyms: 4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexanone;4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexan-1-one
• CAS NO: 471903-20-5
• Molecular Formula: C₁₈H₁₅ClF₂O₃S
• Molecular Weight: 384.8247064
• Mol File: 471903-20-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexanone(471903-20-5)
• EPA Substance Registry System: 4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexanone(471903-20-5)

Safety Data

• Hazardous Substances Data: 471903-20-5(Hazardous Substances Data)

Upstream product

• 852312-96-0 5-(4-chloro-benzenesulfonyl)-5-(2,5-difluoro-phenyl)-2-oxo-cyclohexanecarboxylic acid methyl ester 
• 470716-52-0 2-[[(4-chlorophenyl)thio]methyl]-1,4-difluorobenzene 
• 470716-51-9 2-[[(4-chlorophenyl)sulfonyl]methyl]-1,4-difluorobenzene 
• 471905-61-0 2-[1-[(4-chlorophenyl)sulfonyl]ethenyl]-1,4-difluorobenzene 
• 106-54-7 p-Chlorothiophenol 
• 85117-99-3 2-(bromomethyl)-1,4-difluorobenzene 
• 471903-19-2 5-(4-chloro-benzenesulfonyl)-5-(2,5-difluoro-phenyl)-2-hydroxy-cyclohex-1-enecarboxylic acid methyl ester 

Downstream Products

• 471903-41-0 trans-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 471905-53-0 cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 471903-66-9 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexylidene]-acetic acid ethyl ester 
• 894853-74-8 (2R,4S)-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-2-[2-(trimethylsilyl)ethoxymethyl]cyclohexanone 
• 656810-84-3 [4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexylidene]acetonitrile 
• 471905-62-1 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-en-1-yl trifluoromethanesulfonate 
• 471905-01-8 cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexylacetonitrile 
• 656810-85-4 cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexylacetaldehyde 
• 656810-86-5 cis-1-[4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-3-propanal 
• 471905-41-6 3-((1S,4R)-4-((4-chlorophenyl)sulfonyl)-4-(2,5- difluorophenyl)cyclohexyl)propanoic acid 
• 942296-40-4 3-[4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-enyl]propanoic acid 

Relevant articles and documents

Sulphonamido-Substituted Cyclohexyl Sulphones for Treatment of Cancer

Compounds of formula (I) are disclosed for treatment of cancer.

CYCLOHEXYL SULPHONES FOR TREATMENT OF CANCER

Sulphones of formula (I) are disclosed for use in treatment of cancer.

The new cyclohexylpropionic sulfone

Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.