482378-37-0

Basic information

• Product Name: 1-{4-[4-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butoxy]-5-methoxy-2-nitro-benzoyl}-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 482378-37-0
• Molecular Weight: 575.575
• Mol File: 482378-37-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{4-[4-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butoxy]-5-methoxy-2-nitro-benzoyl}-pyrrolidine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{4-[4-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butoxy]-5-methoxy-2-nitro-benzoyl}-pyrrolidine-2-carboxylic acid methyl ester(482378-37-0)
• EPA Substance Registry System: 1-{4-[4-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butoxy]-5-methoxy-2-nitro-benzoyl}-pyrrolidine-2-carboxylic acid methyl ester(482378-37-0)

Safety Data

• Hazardous Substances Data: 482378-37-0(Hazardous Substances Data)

Upstream product

• 58895-73-1 N-(4-bromobutyl)-1,8-naphthalimide 
• 175409-49-1 methyl-(2S)-N-[4-hydroxy-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxylate 
• 140646-99-7 (S)-methyl 1-(4-(benzyloxy)-5-methoxy-2-nitrobenzoyl)pyrrolidine-2-carboxylate 
• 64154-79-6 (2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)pyrrolidine-2-carboxylic acid 
• 1486-53-9 4-(benzyloxy)-3-methoxybenzoic acid 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 64154-78-5 4-benzyloxy-5-methoxy-2-nitrobenzoyl chloride 
• 60547-92-4 4-(benzyloxy)-5-methoxy-2-nitrobenzoic acid 
• 81-84-5 1,8-Naphthalic anhydride 
• 81-83-4 1,8-Naphthalimide 

Relevant articles and documents

Design and synthesis of C-8 linked pyrrolobenzodiazepine-naphthalimide hybrids as anti-tumour agents

The facile synthesis of C-8 linked pyrrolobenzodiazepine-naphthalimide hybrid analogues is described. The compounds are prepared with varying degrees of linker length in order to probe the structural requirements for optimal in vitro anti-tumour activity. Some of these new hybrid compounds showed higher cytotoxic activity than the existing natural and synthetic pyrrolo[2,1-c][1,4]benzodiazepines.