492456-51-6

Basic information

• Product Name: 2-Propenoic acid, 2-cyano-3-[(3-ethoxy-4-nitrophenyl)amino]-, ethyl ester
• CAS NO: 492456-51-6
• Molecular Formula: C14H15N3O5
• Molecular Weight: 305.29
• Mol File: 492456-51-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-cyano-3-[(3-ethoxy-4-nitrophenyl)amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-cyano-3-[(3-ethoxy-4-nitrophenyl)amino]-, ethyl ester(492456-51-6)
• EPA Substance Registry System: 2-Propenoic acid, 2-cyano-3-[(3-ethoxy-4-nitrophenyl)amino]-, ethyl ester(492456-51-6)

Safety Data

• Hazardous Substances Data: 492456-51-6(Hazardous Substances Data)

Upstream product

• 361162-91-6 5-ethoxy-2-methyl-4-nitroacetanilide 
• 361162-90-5 5-methoxy-2-methyl-4-nitroacetanilide 
• 106579-00-4 5-methoxy-2-methyl-4-nitroaniline 
• 116435-75-7 3-(ethyloxy)-4-nitroaniline 
• 94-05-3 2-cyano-3-ethoxyacrylic acid ethyl ester 

Downstream Products

• 214476-08-1 7-Ethoxy-4-hydroxy-6-nitro-quinoline-3-carbonitrile 
• 257933-82-7 pelitinib 
• 492456-86-7 N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-2-butenamide 
• 361162-95-0 6-amino-4-(3-chloro-4-fluoro-phenylamino)-7-ethoxy-quinoline-3-carbonitrile 
• 214485-68-4 4-(3-Bromo-phenylamino)-7-ethoxy-6-nitro-quinoline-3-carbonitrile 
• 214485-69-5 6-amino-4-(3-bromo-phenylamino)-7-ethoxy-quinoline-3-carbonitrile 
• 214476-09-2 4-Chloro-7-ethoxy-6-nitro-quinoline-3-carbonitrile 

Relevant articles and documents

Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the human epi

A series of of 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile derivatives that function as irreversible inhibitors of EGFR and HER-2 kinases have been prepared. These inhibitors have, at the 6-position, butynamide, crotonamide, and methacrylamide Mic