494799-22-3 Usage
General Description
Methyl 2-bromo-3-cyclohexyl-1-methyl-1H-indole-6-carboxylate is a chemical compound with the molecular formula C17H20BrNO2. It is a derivative of indole, a heterocyclic organic compound, and contains a bromine atom, a methyl group, and a cyclohexyl group attached to the indole ring. Methyl 2-broMo-3-cyclohexyl-1-Methyl-1H-indole-6-carboxylate is commonly used in organic synthesis and pharmaceutical research due to its potential biological activity and structural significance. Its unique structure and functional groups make it a valuable building block for the synthesis of various biologically active compounds and potential drug candidates. Additionally, it may also have applications in the fields of material science and agrochemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 494799-22-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,4,7,9 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 494799-22:
(8*4)+(7*9)+(6*4)+(5*7)+(4*9)+(3*9)+(2*2)+(1*2)=223
223 % 10 = 3
So 494799-22-3 is a valid CAS Registry Number.
494799-22-3Relevant articles and documents
Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds
Beaulieu, Pierre L.,Gillard, James,Bykowski, Darren,Brochu, Christian,Dansereau, Nathalie,Duceppe, Jean-Simon,Hache, Bruno,Jakalian, Araz,Lagace, Lisette,LaPlante, Steven,McKercher, Ginette,Moreau, Elaine,Perreault, Stephane,Stammers, Timothy,Thauvette, Louise,Warrington, Jeff,Kukolj, George
, p. 4987 - 4993 (2007/10/03)
Benzimidazole-based allosteric inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified to a variety of topologically related scaffolds. Replacement of the polar benzimidazole core by lipophilic indoles led to inhibitors with improved potency in the cell-based subgenomic HCV replicon system. Transposing the indole scaffold into a previously described series of benzimidazole-tryptophan amides generated the most potent inhibitors of HCV RNA replication in cell culture reported to date in this series (EC50 ～ 50 nM).
