49565-61-9 Usage
Derivative of benzoic acid
2-(ethylamino)-4-nitrobenzoic acid is derived from benzoic acid, which is a simple aromatic carboxylic acid.
Nitro group
The compound contains a nitro group (-NO2) attached to the benzene ring, which contributes to its chemical reactivity and properties.
Ethylamino group
The compound also contains an ethylamino group (-NHCH2CH3) attached to the benzene ring, which influences its chemical properties and reactivity.
Use in synthesis
2-(ethylamino)-4-nitrobenzoic acid is often used as an intermediate in the synthesis of pharmaceuticals and dyes due to its reactive functional groups.
pH-sensitive fluorescent probe
The compound exhibits changes in fluorescence intensity depending on the pH of its environment, making it a useful tool in biochemical and pharmacological research.
Antimicrobial properties
2-(ethylamino)-4-nitrobenzoic acid has been found to possess antimicrobial activity, which could be useful in the development of new drugs to combat infections.
Anti-inflammatory properties
The compound also exhibits anti-inflammatory properties, which may make it a potential candidate for the development of new drugs to treat inflammation-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 49565-61-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,5,6 and 5 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 49565-61:
(7*4)+(6*9)+(5*5)+(4*6)+(3*5)+(2*6)+(1*1)=159
159 % 10 = 9
So 49565-61-9 is a valid CAS Registry Number.
49565-61-9Relevant articles and documents
Functionalization of quinazolin-4-ones part 1: Synthesis of novel 7-substituted-2-thioxo quinazolin-4-ones from 4-substituted-2-aminobenzoic acids and PPh3(SCN)2
Heppell, Jacob,Al-Rawi, Jasim
, p. 162 - 174 (2014/02/14)
4-(Nitro, amino, acetylamino)-2-aminobenzoic acid were allowed to react with PPh3(SCN)2 and gave the crossholding 7-nitro, 7-acetylamino- and 7-amino-2-thioxo quinazolin-4-ones respectively. The nature of the substituent at position 4 of the 2-aminobenzoic acids has significant influence on the outcome of the cyclisation reaction with PPh 3(SCN)2. Similarly, the nature of the substituent at position 7 of the 2-substituted quinazolin-4-ones significantly affected the ease with which alkylation reactions could be performed. The alkylation selectivity of the 7- substiuted-2-thioxo quinazolin-4-ones was found to depend on the nature of the alkyl halide and the nature of the substituent at position 2.
