49759-64-0

Basic information

• Product Name: CBZ-L-3-FLUOROPHENYLALANINE
• Synonyms: N-Benzyloxycarbonyl-3-(3-fluorophenyl)-L-alanine;(S)-2-(((Benzyloxy)carbonyl)aMino)-3-(3-fluorophenyl)propanoic acid
• CAS NO: 49759-64-0
• Molecular Formula: C₁₇H₁₆FNO₄
• Molecular Weight: 317.32
• Mol File: 49759-64-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CBZ-L-3-FLUOROPHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: CBZ-L-3-FLUOROPHENYLALANINE(49759-64-0)
• EPA Substance Registry System: CBZ-L-3-FLUOROPHENYLALANINE(49759-64-0)

Safety Data

• Hazardous Substances Data: 49759-64-0(Hazardous Substances Data)

Usage

General Description

CBZ-L-3-Fluorophenylalanine is a chemical compound used in the field of chemistry and biochemistry. It is a derivative of the amino acid phenylalanine, with a fluorine atom attached to the phenyl ring. The compound is often used as a building block in peptide synthesis, allowing for the creation of modified peptides with specific properties or functions. It has also been studied for its potential use in pharmaceuticals and drug development, due to its effects on protein structure and function. Overall, CBZ-L-3-Fluorophenylalanine is a versatile compound with various applications in the scientific and medical fields.

Upstream product

• 49759-56-0 Z-DL-Phe(3F)-OMe 
• 19883-77-3 L-3-fluorophenylalanine 
• 501-53-1 benzyl chloroformate 
• 37447-35-1 2-benzyloxycarbonylaminomalonic acid dimethyl ester 
• 49864-42-8 2-Benzyloxycarbonylamino-2-(3-fluoro-benzyl)-malonic acid monomethyl ester 
• 49759-51-5 2-Benzyloxycarbonylamino-2-(3-fluoro-benzyl)-malonic acid dimethyl ester 
• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 
• 127862-80-0 Z-DL-Phe(3F)-OCH₂CF₃ 

Downstream Products

• 87184-30-3 Cbz-L-m-FPhe-L-Ala-OBzl 
• 87184-27-8 Cbz-L-m-FPhe-L-Ala-L-Ala-OBzl 
• 19883-77-3 L-3-fluorophenylalanine 
• 87184-20-1 L-m-FPhe-L-Ala 
• 87184-16-5 L-m-FPhe-L-Ala-L-Ala 
• 205493-82-9 (3S,4S)-3-{N-benzyloxycarbonyl-β-(3-fluorophenyl)-L-alanyl}-amino-4-acetoxy-azetidin-2-one 

Relevant articles and documents

Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors

ATG4B or autophagin-1 is a cysteine protease that cleaves ATG8 family proteins. ATG4B plays essential roles in the autophagosome formation and the autophagy pathway. Herein we disclose the design and structural modifications of a series of fluoromethylketone (FMK)-based peptidomimetics as highly potent ATG4B inhibitors. Their structure-activity relationship (SAR) and protease selectivity are also discussed.

Porcine Pancreatic Lipase Catalyzed Enantioselective Hydrolysis of Esters of N-Protected Unusual Amino Acids

Porcine pancreatic lipase catalyzed the highly enantioselective hydrolysis of a kind of α-substituted carboxylic esters, i.e., the 2,2,2-trifluoroethyl esters of the N-benzyloxycarbonyl derivatives of unusual amino acids.