500149-85-9Relevant articles and documents
On the para-selective chlorination of ortho-cresol
Bugnet, Emmanuelle A,Brough, Adrian R,Greatrex, Robert,Kee, Terence P
, p. 8059 - 8065 (2002)
Merrifield-bound o-cresol undergoes electrophilic aromatic chlorination using SO2Cl2 leading to para/ortho ratios in excess of 50, the highest such ratio reported for this chlorinating agent. Model studies suggest that this significant para/ortho ratio results not just from steric effects but that considerable electronic influence can be detected.