513068-89-8

Basic information

• Product Name: 4-(4-bromo-2-fluorophenyl)morpholine
• Synonyms: 4-(4-bromo-2-fluorophenyl)morpholine
• CAS NO: 513068-89-8
• Molecular Formula: C₁₀H₁₁BrFNO
• Molecular Weight: 260
• Mol File: 513068-89-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 332.5±42.0 °C(Predicted)
• Appearance: /
• Density: 1.502±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 4.14±0.40(Predicted)
• CAS DataBase Reference: 4-(4-bromo-2-fluorophenyl)morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-bromo-2-fluorophenyl)morpholine(513068-89-8)
• EPA Substance Registry System: 4-(4-bromo-2-fluorophenyl)morpholine(513068-89-8)

Safety Data

• Hazardous Substances Data: 513068-89-8(Hazardous Substances Data)

Usage

Uses

4-(4-Bromo-2-fluorophenyl)morpholine used in the synthesis of oxazolidinone antibacterials.

InChI:InChI=1S/C10H11BrFNO/c11-8-1-2-10(9(12)7-8)13-3-5-14-6-4-13/h1-2,7H,3-6H2

Upstream product

• 93246-53-8 3-fluoro-4-(morpholinyl)aniline 
• 367-24-8 4-bromo-2-fluoroaniline 
• 111-44-4 3-oxa-1,5-dichloropentane 
• 110-91-8 morpholine 
• 105931-73-5 1-bromo-3-fluoro-4-iodobenzene 
• 1073-06-9 3-fluorobromobenzene 
• 369-34-6 3,4-difluoronitrobenzene 
• 2689-39-6 3-fluoro-4-(4-morpholinyl)nitrobenzene 

Downstream Products

• 513068-92-3 3-{3-fluoro-4-morpholinophenyl}-5-(tetrahydro-2H-2-pyranyloxy-methyl)-2-oxazolidinone 
• 513068-96-7 3-(3-fluoro-4-morpholin-4-yl-phenyl)-5-hydroxymethyl-oxazolidin-2-one 
• 224323-50-6 linezolid 
• 858344-36-2 methanesulfonic acid 3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-oxazolidin-5-ylmethyl ester 
• 168828-84-0 (R)-5-azidomethyl-3-(3-fluoro-4-(morpholin-4-yl)phenyl)oxazolidin-2-one 
• 168828-89-5 2-({(5S)-2-oxo-3-[(4-morpholino-3-fluorophenyl)]-4,5-dihydro-1,3-oxazole-5-yl}methyl)-isoindole-1,3-dione 
• 1351994-58-5 3-[3-fluoro-4-(morpholin-4-yl)phenyl]-5-{[(1-phenylethyl)amino]methyl}-1,3-oxazolidin-2-one 
• 1401100-54-6 4-(2-fluoro-4-vinylphenyl)morpholine 

Relevant articles and documents

Novel Linezolid analogues with antiparasitic activity against Hymenolepis nana

The stereoselective synthesis and anti- Hymenolepis nana activity of six Linezolid-type compounds, obtained by chemical modification of L-Alanine, are reported in this work. The synthetic strategy was to prepare diasteromeric N,N-dibenzylamino oxazolidino

ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS

The present invention provides cyclic depsipeptide compounds of formula (I) wherein the stereochemical configuration of at least one carbon atom bearing the groups Cy1, Cy2, R1, R2, R3, R4, Ra and Rb is inverted compared with the naturally occurring cyclic depsipeptide PF1022A. The invention also provides compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.

ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS

The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.