5132-81-0 Usage
Description
Methyl 9-Acridinecarboxylate, with the CAS number 5132-81-0, is a chemical compound that is characterized as a yellow solid. It is primarily known for its utility in the field of organic synthesis, where it serves as a valuable intermediate or building block for the creation of more complex molecules.
Uses
Used in Organic Synthesis:
Methyl 9-Acridinecarboxylate is used as a synthetic intermediate for the production of various organic compounds. Its chemical structure allows it to be a versatile component in the synthesis of a wide range of molecules, including pharmaceuticals, dyes, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 9-Acridinecarboxylate is used as a key component in the development of new drugs. Its unique chemical properties make it a valuable asset in the design and synthesis of novel therapeutic agents, potentially leading to the discovery of new treatments for various diseases and medical conditions.
Used in Dye Manufacturing:
Methyl 9-Acridinecarboxylate is also utilized in the manufacturing of dyes, where its yellow solid form contributes to the color properties of the final product. Its use in this industry highlights the compound's versatility and the broad range of applications it can be employed in.
Used in Research and Development:
In addition to its practical applications, Methyl 9-Acridinecarboxylate is also used in research and development settings. Scientists and chemists employ this compound to study its properties and explore its potential in creating new materials and compounds with unique characteristics and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5132-81-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,3 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5132-81:
(6*5)+(5*1)+(4*3)+(3*2)+(2*8)+(1*1)=70
70 % 10 = 0
So 5132-81-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H11NO2/c1-18-15(17)14-10-6-2-4-8-12(10)16-13-9-5-3-7-11(13)14/h2-9H,1H3
5132-81-0Relevant articles and documents
Metal Ion Assisted DNA-Intercalation of Crown Ether-linked Acridine Derivatives
Fukuda, Ryuji,Takenaka, Shigeori,Takagi, Makoto
, p. 1028 - 1030 (1990)
Crown ether linked DNA-intercalators have shown an enhanced binding ability to DNA in the presence of certain kinds of metal ions, due to a cationic property given by the co-ordination of the crown ether moiety to the metal ions.
Method for preparing 9-hydroxymethyl-9,10-dihydracridine
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Paragraph 0030-0034; 0040-0049, (2019/10/01)
The invention relates to a method for preparing 9-hydroxymethyl-9,10-dihydracridine. The preparation method comprises the following steps: carrying out a reduction reaction on acridine esters shown as a formula (I) in a solvent containing a Lewis acid and a reducing agent so as to produce the 9-hydroxymethyl-9,10-dihydracridine. In the formula (I), R is C1-3 alkyl. The method for preparing 9-hydroxymethyl-9,10-dihydracridine provided by the invention has the advantages that the acridine esters serve as initial raw materials, and due to selection of the raw materials, ester groups and carbon-nitrogen double bonds having equivalent reduction difficulty participate in the reduction reaction, so that selectivity of the reduction reaction is improved, side reactions are reduced, and the reaction yield is improved.
Facile synthesis of unsymmetrical acridines and phenazines by a Rh(III)-catalyzed amination/cyclization/aromatization cascade
Lian, Yajing,Hummel, Joshua R.,Bergman, Robert G.,Ellman, Jonathan A.
supporting information, p. 12548 - 12551 (2013/09/23)
We report formal [3 + 3] annulations of aromatic azides with aromatic imines and azobenzenes to give acridines and phenazines, respectively. These transformations proceed through a cascade process of Rh(III)-catalyzed amination followed by intramolecular electrophilic aromatic substitution and aromatization. Acridines can be directly prepared from aromatic aldehydes by in situ imine formation using catalytic benzylamine.
