52428-09-8

Basic information

• Product Name: 4 7-DIMETHOXY-1-INDANONE 97
• Synonyms: 4 7-DIMETHOXY-1-INDANONE 97;4,7-DIMETHOXY-2,3-DIHYDRO-1H-INDEN-1-ONE;2,3-Dihydro-4,7-dimethoxy-1H-inden-1-one;4,7-DIMETHOXY-2,3-DIHYDROINDEN-1-ONE;4,7-dimethoxy-1H-inden-1-one
• CAS NO: 52428-09-8
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Product Categories: C11 to C12;Carbonyl Compounds;Ketones
• Mol File: 52428-09-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 122-125 °C(lit.)
• Boiling Point: 352.6 ºC at 760 mmHg
• Flash Point: 158.3 ºC
• Appearance: /
• Density: 1.179
• Vapor Pressure: 3.79E-05mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4 7-DIMETHOXY-1-INDANONE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 4 7-DIMETHOXY-1-INDANONE 97(52428-09-8)
• EPA Substance Registry System: 4 7-DIMETHOXY-1-INDANONE 97(52428-09-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 52428-09-8(Hazardous Substances Data)

Usage

Description

4,7-Dimethoxy-1-indanone 97 is an organic compound with the molecular formula C10H10O3. It is characterized by its indanone core structure, which is a seven-membered ring with a ketone group, and two methoxy groups attached to the 4th and 7th positions. 4 7-DIMETHOXY-1-INDANONE 97 is known for its potential applications in various fields due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
4,7-Dimethoxy-1-indanone 97 is used as a reagent for the synthesis and biological evaluation of indenopyrazine dicarbonitrile. 4 7-DIMETHOXY-1-INDANONE 97 serves as an inhibitor of deubiquitinating enzymes, which are crucial in various cellular processes, including protein homeostasis and signal transduction. By targeting these enzymes, 4,7-Dimethoxy-1-indanone 97 can potentially contribute to the development of novel therapeutic strategies for various diseases, including cancer and neurodegenerative disorders.

InChI:InChI=1/C11H12O3/c1-13-9-5-6-10(14-2)11-7(9)3-4-8(11)12/h5-6H,3-4H2,1-2H3

Upstream product

• 10538-49-5 3-(2,5-dimethoxyphenyl)propanoic acid 
• 71-43-2 benzene 
• 100126-94-1 3-(2,5-dimethoxyphenyl)propionyl chloride 
• 2680-03-7 N,N-Dimethylacrylamide 
• 150-78-7 1,4-dimethoxybezene 
• 848610-51-5 5-(2,5-dimethoxybenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 38489-74-6 trans-2,5-dimethoxycinnamic acid 
• 10538-51-9 2,5-dimethoxycinnamic acid 

Downstream Products

• 65698-22-8 4,7-dihydroxy-2,3-dihydro-1H-inden-1-one 
• 134663-13-1 1-(but-3-enyl)-4,7-dimethoxyindan-1-ol 
• 78572-95-9 4,7-dimethoxy-3-methylindene 
• 123676-79-9 5'-bromo-4,7-dimethoxy-2,2'-spirobiindan-1-one 
• 98154-04-2 7-hydroxy-4-methoxy-2,3-dihydroinden-1-one 
• 78907-19-4 4,7-dimethoxy-1-indanol 
• 22065-52-7 (±)-methyl 4,7-dimethoxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate 
• 111670-02-1 4,7-dimethoxy-1-ethynyl-1-indanol 
• 81664-67-7 2-carbethoxy-2,3-dihydro-4,7-dimethoxy-1H-inden-1-one 
• 157793-83-4 4'-bromo-4,7-dimethoxy-2,2'-spirobiindan-1-one 
• 162019-02-5 4,7-dimethoxy-6-(2,4,5-trichloro-3,6-dimethoxybenzyl)indanone 
• 174228-70-7 [4,7-Dimethoxy-1-oxo-indan-(2E)-ylidene]-acetic acid 
• 38998-05-9 4,7-dimethoxyindane 
• 16101-70-5 2-oxyimino-4,7-dimethoxy-1-indanone 

Relevant articles and documents

Stereoselective Synthesis of [4.3.1]Propellane Fragment of Phainanoids A–F

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SPIRO COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS

Disclosed are spiro compounds of formula (I), or stereomers, geometric isomers, tautomers, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof. The compounds can be used to treat hepatitis C virus (HCV) infection or hepatitis C disease. Furthermore disclosed are pharmaceutical compositions containing the compounds and the method of using the compounds or pharmaceutical compositions in the treatment of HCV infection or hepatitis C disease.

SPIRO RING COMPOUND AS HEPATITIS C VIRUS (HCV) INHIBITOR AND USES THEREOF FIELD OF THE INVENTION

A compound of formula (I) or a stereoisomer, a geometric isomer. a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof is provided, which can be used for treating HCV infection or a HCV disorder. Also a pharmaceutical composition comprising the compound and the use of the compound and the pharmaceutical composition thereof are provided, which can also be used for treating HCV infection or a HCV disorder.