52750-05-7

Basic information

• Product Name: 2-propenoic acid, 3-(4-methoxyphenyl)-2-methyl-, ethyl ester
• Synonyms: Ethyl 3-(4-methoxyphenyl)-2-methylacrylate
• CAS NO: 52750-05-7
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.2643
• Mol File: 52750-05-7.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 333.448°C at 760 mmHg
• Flash Point: 137.693°C
• Density: 1.063g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.533
• CAS DataBase Reference: 2-propenoic acid, 3-(4-methoxyphenyl)-2-methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-propenoic acid, 3-(4-methoxyphenyl)-2-methyl-, ethyl ester(52750-05-7)
• EPA Substance Registry System: 2-propenoic acid, 3-(4-methoxyphenyl)-2-methyl-, ethyl ester(52750-05-7)

Safety Data

• Hazardous Substances Data: 52750-05-7(Hazardous Substances Data)

Upstream product

• 27961-57-5 3-hydroxy-3-(4-methoxy-phenyl)-2-methyl-propionic acid ethyl ester 
• 123-11-5 4-methoxy-benzaldehyde 
• 535-11-5 Ethyl 2-bromopropionate 
• 3699-66-9 ethyl 2-diethoxyphosphorylpropionate 
• 172427-71-3 ethyl <2R,4R>-2-(4-methoxyphenyl)-α-oxo-1,3-dioxane-4-acetate 
• 10025-87-3 trichlorophosphate 
• 21382-82-1 (carbethoxyethylidene)triphenylphosphorane 
• 824-94-2 p-methoxybenzyl chloride 
• 135362-69-5 3-(4-methoxybenzyl)oxypropan-1-ol 
• 172427-68-8 ethyl <2E>-5-(4-methoxybenzyloxy)-2-pentenoate 
• 172427-69-9 ethyl <2S,3R>-2,3-dihydroxy-5-(4-methoxybenzyloxy)pentanoate 
• 172427-70-2 ethyl <αS,2S,4R>-α-hydroxy-2-(4-methoxyphenyl)-1,3-dioxane-4-acetate 
• 97-63-2 methyl methacrylate 
• 101834-91-7 chloro-2 phosphono-2 propionate de triethyle 

Downstream Products

• 40527-52-4 3-(4-anisyl)-2-methylacrylic acid 
• 52750-06-8 ethyl 2-methyl-3-[4-(methoxy)phenyl]propanoate 
• 64506-21-4 (+/-)-2-methyl-3-(p-methoxyphenyl)propanol 
• 91970-30-8 (E)-3-(4-Methoxyphenyl)-2-methylprop-2-en-1-ol 
• 56935-39-8 α-methyl-β-(p-methoxyphenyl)-propionyl chloride 
• 64-13-1 2-amino-1-(4-methyoxyphenyl)propane 
• 52427-11-9 3-(4-methoxyphenyl)-2-methylpropionic acid 
• 39755-38-9 3-(4'-methoxyphenyl)-2-methyl-propanamide 
• 103305-40-4 (2S,3S)-3-(4-Methoxy-phenyl)-2,4-dimethyl-pent-4-enoic acid ethyl ester 
• 103305-40-4 (2R,3S)-3-(4-Methoxy-phenyl)-2,4-dimethyl-pent-4-enoic acid ethyl ester 
• 103305-41-5 (2R,3S)-2-Ethyl-3-(4-methoxy-phenyl)-4-methyl-pent-4-enoic acid methyl ester 
• 103305-41-5 (2S,3S)-2-Ethyl-3-(4-methoxy-phenyl)-4-methyl-pent-4-enoic acid methyl ester 
• 115753-99-6 2-methyl-3(4'-methoxy-1'-phenyl)allyl bromide 
• 1262899-34-2 (S)-(+)-ethyl 3-(4-methoxyphenyl)-2-methylpropanoate 

Relevant articles and documents

Copper-Photocatalyzed Contra-Thermodynamic Isomerization of Polarized Alkenes

The contra-thermodynamic isomerization of α- and β-substituted cinnamate derivatives catalyzed by the Cu(OAc)2/rac-BINAP complex under blue light irradiation is reported. The use of an oxazolidinone template, which favored the complexation of the copper catalyst to the substrate, allowed the E → Z isomerization of the catalytically formed chromophore under simple and robust reaction conditions in good to excellent ratios. The mechanism of this process based on the transient formation of a chromophore was also studied.

Synthesis of α,β-Disubstituted Acrylates via Galat Reaction

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Control of Chemo-, Regio-, and Enantioselectivity in Copper Hydride Reductions of Morita-Baylis-Hillman Adducts

Nonracemically ligated copper hydride can be used to effect tandem SN2′/1,2-reductions of racemic Morita-Baylis-Hillman (MBH) acetates to access enantioenriched chiral allylic alcohols with defined olefin geometry. MBH esters, including those w