5315-24-2

Basic information

• Product Name: 2-METHYL-6-HYDRAZINOPYRIDINE
• Synonyms: 2-METHYL-6-HYDRAZINOPYRIDINE;2-Hydrazinyl-6-methylpyridine;2-hydrazino-6-methylpyridine(SALTDATA: 1.3HCl 0.7H2O);Pyridine, 2-hydrazinyl-6-methyl-;2-Hydrazinyl-6-Methylpyridine(WXC01942)
• CAS NO: 5315-24-2
• Molecular Formula: C₆H₉N₃
• Molecular Weight: 123.16
• Product Categories: Heterocycle-Pyridine series;amine
• Mol File: 5315-24-2.mol
• Article Data: 13

Chemical Properties

• Melting Point: 54-56 °C
• Boiling Point: 262.196°C at 760 mmHg
• Flash Point: 112.372°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.633
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 9.73±0.70(Predicted)
• CAS DataBase Reference: 2-METHYL-6-HYDRAZINOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-6-HYDRAZINOPYRIDINE(5315-24-2)
• EPA Substance Registry System: 2-METHYL-6-HYDRAZINOPYRIDINE(5315-24-2)

Safety Data

• Hazardous Substances Data: 5315-24-2(Hazardous Substances Data)

Usage

General Description

2-Methyl-6-hydrazinopyridine, also known as Lepephyrin or LEP, is a chemical compound with the molecular formula C6H8N4. It is a hydrazine derivative that is used in the synthesis of pharmaceuticals and agrochemicals. 2-Methyl-6-hydrazinopyridine has been studied for its potential use as a corrosion inhibitor and as a precursor to a range of heterocyclic compounds. It is also known for its ability to complex with metal ions, making it useful in coordination chemistry. Additionally, this compound has been researched for its anti-tumor and anti-cancer properties, demonstrating its potential as a valuable tool in medicinal chemistry.

InChI:InChI=1/C6H9N3/c1-5-3-2-4-6(8-5)9-7/h2-4H,7H2,1H3,(H,8,9)

Upstream product

• 5315-25-3 2-bromo-6-methylpyridine 
• 407-22-7 2-fluoro-6-methylpyridine 
• 18368-63-3 6-chloro-2-picoline 
• 38557-71-0 2-chloro-6-methylpyrazine 

Downstream Products

• 701979-19-3 4-[1-(6-methyl-pyridin-2-yl)-5-quinoxalin-6-yl-1H-[1,2,4]triazol-3-yl]-benzonitrile 
• 957655-81-1 C₂₃H₁₈N₄O₂ 
• 1431142-72-1 C₂₇H₂₄Cl₂F₃N₇O₂ 
• 1427301-11-8 C₂₂H₁₆Cl₂F₃N₇ 
• 723286-86-0 3-(trifluoromethyl)-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine 
• 4926-18-5 5-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 4926-14-1 5-methyl-3-phenyl-[1,2,4]triazolo[4,3-a]pyridine 
• 96206-92-7 2-methyl-6-(phenylethynyl)pyridine 
• 5528-51-8 5-methyl-[1,2,4]triazolo[4,3-a]pyridine 

Relevant articles and documents

Pyrazolo-cyclic compound, pharmaceutical composition containing pyrazolo-cyclic compound, and preparation method and application of pyrazolo-cyclic compound

The invention belongs to the field of medicinal chemistry, and relates to a pyrazolo-cyclic compound, a pharmaceutical composition containing the pyrazolo-cyclic compound, and a preparation method and application of the pyrazolo-cyclic compound. Specifica

5-(4-PYRIDYLOXY)PYRAZOLE COMPOUNDS SERVING AS TGF-BETA R1 KINASE INHIBITOR

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Metal free [4+1] and [5+1] annulation reactions to prepare heterocycles using DMF and its derivatives as one-carbon source

1,2,4-Triazolo[3,4-a]pyridines and related heterocycles and substituted triazines were commonly discovered scaffolds in a variety of pharmaceutical and agrochemical agents. Herein, we report a highly efficient and practical method using DMF and its derivative for the [4+1] and [5+1] annulation reactions to prepare these heterocycles. This metal free reaction takes advantages of shelf stable DMF as solvent and carbon donor, imidazole chloride as a catalyst, the mild reaction condition tolerates a broad substrate range and substitutes. The prepared 3-unsubstituted 1,2,4-triazolo[3,4-a]pyridine and derivatives allow further introduction of a variety of functional group1 at 3-position.