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536761-10-1

536761-10-1

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536761-10-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 536761-10-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,6,7,6 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 536761-10:
(8*5)+(7*3)+(6*6)+(5*7)+(4*6)+(3*1)+(2*1)+(1*0)=161
161 % 10 = 1
So 536761-10-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H9ClFNO2/c16-10-6-5-9(13(17)7-10)8-18-14(19)11-3-1-2-4-12(11)15(18)20/h1-7H,8H2

536761-10-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(4-CHLORO-2-FLUOROBENZYL)PHTHALIMIDE

1.2 Other means of identification

Product number -
Other names N-(4-chloro-2-fluoro-benzyl)phthalimide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:536761-10-1 SDS

536761-10-1Relevant articles and documents

Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity

Leonard, Kristi,Marugan, Juan Jose,Raboisson, Pierre,Calvo, Raul,Gushue, Joan M.,Koblish, Holly K.,Lattanze, Jennifer,Zhao, Shuyuan,Cummings, Maxwell D.,Player, Mark R.,Maroney, Anna C.,Lu, Tianbao

, p. 3463 - 3468 (2007/10/03)

The disruption of the p53-Hdm2 protein-protein interaction induces cell growth arrest and apoptosis. We have identified the 1,4-benzodiazepine-2,5-dione scaffold as a suitable template for inhibiting this interaction by binding to the Hdm2 protein. Several compounds have been made with improved potency, solubility, and cell-based activities.

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