53857-10-6

Basic information

• Product Name: 1-Butanone, 4-(2-methyl-1,3-dioxolan-2-yl)-1-phenyl-
• CAS NO: 53857-10-6
• Molecular Formula: C14H18O3
• Molecular Weight: 234.295
• Mol File: 53857-10-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 4-(2-methyl-1,3-dioxolan-2-yl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 4-(2-methyl-1,3-dioxolan-2-yl)-1-phenyl-(53857-10-6)
• EPA Substance Registry System: 1-Butanone, 4-(2-methyl-1,3-dioxolan-2-yl)-1-phenyl-(53857-10-6)

Safety Data

• Hazardous Substances Data: 53857-10-6(Hazardous Substances Data)

Upstream product

• 5978-08-5 1-chloro-4-(1,3-dioxolane)-n-pentane 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 87109-17-9 1-diphenylphosphinoyl-4-(2-methyl-[1,3]dioxolan-2-yl)-propane 
• 93-58-3 benzoic acid methyl ester 
• 87109-34-0 2-diphenylphosphinoyl-4-(2-methyl-[1,3]dioxolan-2-yl)-1-phenyl-butan-1-one 
• 108-86-1 bromobenzene 
• 56881-73-3 1-(3-cyanopropyl)-1-methyl-2,5-dioxolane 
• 100-47-0 benzonitrile 
• 98-88-4 benzoyl chloride 
• 3389-54-6 n-benzoylpyrrolidine 

Downstream Products

• 6303-82-8 1-phenylhexane-1,5-dione 
• 1075724-33-2 ethyl 6-(2-methyl-1,3-dioxolan-2-yl)-3-phenylhex-2-enoate 

Relevant articles and documents

CuH-catalyzed enantioselective intramolecular reductive aldol reactions generating three new contiguous asymmetric stereocenters

Treatment of β,β-disubstituted-α,β-unsaturated ketones bearing a ketone residue with in situ generated, catalytic CuH ligated by a nonracemic ligand leads to three newly created adjacent chiral centers. Excellent des and ees are obtained for several examples studied. Copyright

Photoaddition of styrene on certain β-polyketones

The irradiation of 1,5-diphenylpentane-1,3,5-trione 1 and 1-phenylhexane-1,3,5-trione 2 at λ > 290 nm with styrene gives products of double photo-addition: 1,2,6,9-tetraphenylnonane-1,5,9-trione 5 and 1,2,6-triphenyldecane-1,5,9-trione 6, respectively.Under the same conditions with λ > 220 nm, 2-(3-oxo-3-phenylpropionyl)indane-1,3-dione 3 and 2-(3-oxobutyryl)indane-1,3-dione 4 give only products of simple photoaddition: 4-(3-oxo-3-phenylpropionyl)-2-phenylbenzocycloheptane-1,5-dione 7 and 4-(3-oxobutyryl)-2-phenylbenzocycloheptane-1,5-dione 8, respectively.The regiospecificity previously observed with the β-diketones is not a general rule for these β-triketones.The phenyl group in position 6 (products 5 and 6) is not in the α-position of the benzoyl group.The δ-triketones obtained are characterized using β-diketonic models, which are prepared by a simple sequence.Observations of products 7 and 8 show that styrene reacts with the cyclic enol only.This work may be considered as a model study for the prediction of the behavior of triketones 1, 2, 3 and 4 in the side chain of polymeric compounds.Keywords: photoaddition / styrene / β-polyketones / stereoselectivity

2-(3-Lithiopropyl)- and 2-(3-lithiopropyl)-2-methyl-1,3-dioxolane: New masked lithium bishomoenolates in the synthesis of bifunctionalized compounds

2-(3-Lithiopropyl)- and 2-(3-lithiopropyl)-2-methyl-1,3-dioxolane (2) are prepaned by lithiation of the corresponding chlorinated precursors with lithium naphthalenide at -78°C. The reaction of these masked bishomoenolates with different electrophiles yie