54135-81-8

Basic information

• Product Name: (2,3,5-trichlorophenyl)methanol
• Synonyms: (2,3,5-trichlorophenyl)methanol
• CAS NO: 54135-81-8
• Molecular Formula: C₇H₅Cl₃O
• Molecular Weight: 211.47
• Mol File: 54135-81-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 299.4°Cat760mmHg
• Flash Point: 134.9°C
• Appearance: /
• Density: 1.52g/cm³
• Vapor Pressure: 0.000532mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: (2,3,5-trichlorophenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3,5-trichlorophenyl)methanol(54135-81-8)
• EPA Substance Registry System: (2,3,5-trichlorophenyl)methanol(54135-81-8)

Safety Data

• Hazardous Substances Data: 54135-81-8(Hazardous Substances Data)

Usage

Description

(2,3,5-trichlorophenyl)methanol, commonly known as triclosan, is a synthetic chemical compound characterized by its broad-spectrum antibacterial and antifungal properties. It is a white crystalline solid with a chemical formula of C12H7Cl3O2. Triclosan is known for its effectiveness in inhibiting the growth of bacteria and fungi, which has led to its widespread use in various applications.

Uses

Used in Personal Care Products:
Triclosan is used as an active ingredient in personal care products such as soaps, toothpastes, and deodorants. It serves as an antibacterial agent, helping to reduce the growth of bacteria on the skin and in the mouth, thereby promoting better hygiene and preventing infections.
Used in Household and Industrial Products:
In addition to personal care products, triclosan is also used in household and industrial products like cleaning supplies and textiles. Its antibacterial and antifungal properties make it an effective additive in these products, helping to maintain cleanliness and prevent the growth of harmful microorganisms.
However, it is important to note that the use of triclosan has been a subject of controversy due to its potential negative impact on the environment and human health. It has been linked to skin irritation, hormone disruption, and the emergence of antibiotic-resistant bacteria. As a result, many countries have banned or restricted the use of triclosan in consumer products, leading to a decline in its prevalence in the marketplace.

InChI:InChI=1/C7H5Cl3O/c8-5-1-4(3-11)7(10)6(9)2-5/h1-2,11H,3H2

Upstream product

• 634-90-2 1,2,3,5-tetrachlorobenzene 
• 124-41-4 sodium methylate 
• 5472-99-1 3-chloro-2-nitroanisole 
• 933-78-8 2,3,5-trichlorophenol 
• 77-78-1 dimethyl sulfate 
• 18487-39-3 2,3,5-trichloroaniline 
• 825-41-2 3-chloro-4-nitroaniline 
• 588-07-8 3-Chloroacetanilide 
• 34283-94-8 2,3,5-trichloronitrobenzene 
• 62-53-3 aniline 
• 634-93-5 2,4,6-trichloroaniline 

Downstream Products

• 933-78-8 2,3,5-trichlorophenol 
• 86607-58-1 1,2-dichloro-3,5-dimethoxybenzene 
• 10367-97-2 2,5-dichloro-1,3-dimethoxybenzene 
• 150-19-6 O-methylresorcine 

Relevant articles and documents

THE REACTIONS OF UNACTIVATED ARYL HALIDES WITH SODIUM METHOXIDE IN HMPA; SYNTHESIS OF PHENOLS, ANISOLES, AND METHOXYPHENOLS

Sodium methoxide reacts with dichlorobenzenes in HMPA to give the chloroanisoles as a result of a SNAr process.Excess MeONa then effects the demethylation of the ethers to give the chlorophenols via an SN2 reaction.With tri- and tetrachlorobenzenes the initially formed chloroanisoles can be dealkylated to chlorophenols or can suffer further substitution to give the chlorodimethoxybenzenes; these react with excess MeONa to give the chloromethoxyphenols.The results obtained with the various isomers of the di-, tri-, and tetrachlorobenzenes are presented and discussed on the basis of the electronic effects of the substituents.