54916-28-8

Basic information

• Product Name: 4-ACETYL-4'-METHOXYDIPHENYL ETHER
• Synonyms: 1-[4-(4-METHOXYPHENOXY)PHENYL]ETHAN-1-ONE;1-[4-(4-METHOXY-PHENOXY)-PHENYL]-ETHANONE;4-ACETYL-4'-METHOXYDIPHENYL ETHER;BUTTPARK 52\12-18;4-(4-Methoxyphenoxy)acetophenone;1-[4-(4-Methoxyphenoxy)phenyl]ethan-1-on, 97%;1-[4-(4-Methoxyphenoxy)phenyl]-1-ethanone;1-[4-(4-Methoxyphenoxy)phenyl]ethan-1-one, 4-Acetyl-4'-methoxydiphenyl ether
• CAS NO: 54916-28-8
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.27
• Mol File: 54916-28-8.mol
• Article Data: 32

Chemical Properties

• Melting Point: 56-58°C
• Boiling Point: 198-201°C 2mm
• Flash Point: 198-201°C/2mm
• Appearance: /
• Density: 1.123±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2115929
• CAS DataBase Reference: 4-ACETYL-4'-METHOXYDIPHENYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETYL-4'-METHOXYDIPHENYL ETHER(54916-28-8)
• EPA Substance Registry System: 4-ACETYL-4'-METHOXYDIPHENYL ETHER(54916-28-8)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• Hazardous Substances Data: 54916-28-8(Hazardous Substances Data)

Usage

General Description

4-ACETYL-4'-METHOXYDIPHENYL ETHER, also known as aMDE, is a chemical compound with the molecular formula C16H16O3. It is a derivative of diphenoxylic acid and belongs to the class of diphenyl ethers. 4-ACETYL-4'-METHOXYDIPHENYL ETHER is commonly used in organic synthesis and pharmaceutical research due to its diverse properties and potential applications. It has also been investigated for its potential therapeutic effects, particularly in the field of neuropharmacology. Additionally, aMDE has been studied for its antioxidant and antiviral activities, making it a valuable subject of research in the field of medicinal chemistry. Overall, 4-ACETYL-4'-METHOXYDIPHENYL ETHER is a versatile chemical with promising potential in various scientific and medical applications.

Upstream product

• 1655-69-2 1-methoxy-4-phenoxy-benzene 
• 75-36-5 acetyl chloride 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 150-76-5 4-methoxy-phenol 
• 99-90-1 para-bromoacetophenone 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 77-78-1 dimethyl sulfate 
• 1122-95-8 sodium 4-methoxyphenolate 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 139-02-6 sodium phenoxide 
• 99-91-2 para-chloroacetophenone 
• 100-19-6 (4-nitrophenyl)ethanone 
• 13329-40-3 4-Iodoacetophenone 

Downstream Products

• 1215-99-2 1-[4-(4-hydroxy-phenoxy)-phenyl]-ethanone 
• 94311-50-9 2-[4-(4-methoxyphenoxy)phenyl]-1-morpholin-4-yl-ethanethione 
• 116218-30-5 3-Dimethylamino-2-dimethylaminomethyl-1-[4-(4-methoxy-phenoxy)-phenyl]-propan-1-one; hydrochloride 
• 86896-98-2 4-methoxyphenyl 4-(hydroxyisopropyl)phenyl ether 
• 86431-73-4 4-methoxyphenyl 4-(chloroisopropyl)phenyl ether 
• 852631-12-0 [4-(4-methoxyphenoxy)phenyl]acetic acid methyl ester 
• 852631-17-5 [4-(4-methoxyphenoxy)phenyl]malonic dimethyl ester 
• 852631-21-1 5-[4-(4-methoxyphenoxy)phenyl]pyrimidine-2,4,6-trione 
• 852631-26-6 5-bromo-5-[4-(4-methoxyphenoxy)phenyl]pyrimidine-2,4,6-trione 
• 393796-68-4 5-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-5-[4-(4-methoxy-phenoxy)-phenyl]-pyrimidine-2,4,6-trione 
• 92549-44-5 [4-(4-methoxyphenoxy)phenyl]acetic acid 
• 10181-93-8 4-(4-methoxyphenoxy)phenol 
• 257609-02-2 1-(4-(4-(benzyloxy)phenoxy)phenyl)ethan-1-one 
• 620633-63-8 1-(3-Fluoro-phenyl)-3-[4-(4-methoxy-phenoxy)-phenyl]-propane-1,3-dione 

Relevant articles and documents

Nickel-catalyzed denitrative etherification of activated nitrobenzenes

Electron-deficient nitrobenzenes were coupled with phenols/alcohols to form diaryl/alkyl aryl ethers by the aid of NiCl2 as the catalyst. The reactions were conducted under ligand- and oxidant-free conditions without the exclusion of air or moisture. The initial studies upon the mechanism of the reaction revealed two solvent-dependent approaches. In molten TBAB, SNAr mechanism seems to be predominated, while, in DMF, the reaction might include the radical species.

Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides

The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of each group are described in the specification. The compound represented by formula I can be used as a ligand in copper-catalyzed coupling reaction of aryl halides for the formation of C—N, C—O and C—S bonds.

Novel EDA transient electron donor-acceptor complex, and preparation method and applications thereof

The invention relates to a novel EDA transient electron donor-acceptor complex, and a preparation method and applications thereof. The structure of the complex is represented in the description, wherein R1 represents an electron-withdrawing group such as cyano, nitro, acetyl, trifluoromethyl, and the like; R2 represents any one substituent group such as hydrogen, an alkyl group (methyl, ethyl, etc.), chlorine, bromine, iodine, methoxyl, nitro, and the like; and the position of the substituent group can be an o-position, m-position, or p-position. According to the synthesis method, under the induction of visible light, phenol derivatives and electron deficient aryl halide carry out reactions under the action of basic cesium carbonate to generate the complex, and no transition metal catalyst, transition metal ligand, or photo oxidation-reduction agent is added. Through the reaction mechanism, a series of diaryl ether derivatives is prepared. The preparation method has the advantages of mild conditions, greenness, high efficiency, low cost, and simple operation.