564-20-5

Basic information

• Product Name: Sclareolide
• Synonyms: SCLAREOLIDE;1-b]furan-2(1H)-one,decahydro-3a,6,6,9a-tetramethyl-,[3aR-(3a.alpha.,5a.beta.,9a.alpha.,9b.beta.)Naphtho[2;1-b]furan-2(1h)-one,decahydro-3a,6,6,9a-tetramethyl-naphtho[[3atheta-(3a;5abeta,9aalpha,9bbeta)]-alph;Decahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan-2(1H)-one;Norambrienolide;[3aR-(3aalpha,5abeta,9aalpha,9bbeta)]Decahydro-3a,6,6,9a-tetramethylnaphth[2,1-b]furan-2(1H)-one;(3AR)-(+)-SCLAREOLIDE
• CAS NO: 564-20-5
• Molecular Formula: C16H26O2
• Molecular Weight: 250.38
• EINECS: 209-269-0
• Product Categories: Miscellaneous Natural Products;Natural Plant Extract;Flavors & Fragrances;Chiral Building Blocks;Furans;Heterocyclic Building Blocks;Flavors and Fragrances;Inhibitors
• Mol File: 564-20-5.mol
• Article Data: 64

Chemical Properties

• Melting Point: 124-126 °C(lit.)
• Boiling Point: 321.4 °C at 760 mmHg
• Flash Point: 132.4 °C
• Appearance: off-white to white crystal powder
• Density: 1.009 g/cm³
• Vapor Pressure: 0.000299mmHg at 25°C
• Refractive Index: 1.489
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), DMSO (Slightly)
• Water Solubility: 10mg/L at 25℃
• CAS DataBase Reference: Sclareolide(CAS DataBase Reference)
• NIST Chemistry Reference: Sclareolide(564-20-5)
• EPA Substance Registry System: Sclareolide(564-20-5)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 2
• Hazardous Substances Data: 564-20-5(Hazardous Substances Data)

Usage

Chemical Properties

Sclareolide has a musky, wood odor.

Occurrence

Reported present in clary sage bush (Salvia sclarea)

Uses

Different sources of media describe the Uses of 564-20-5 differently. You can refer to the following data:
1. Sclareolide is found in Salvia yosgadensis and is a close analog of sclareol, an antifungal diterpene.
2. antimicrobial
3. sclareolide is a fragrancing ingredient, it can help mask formulation odors. It is synthetically manufactured.

Preparation

Sclareol, isolated from clary sage by solvent extraction, can be efficiently oxidized by the microorganism Cryptococcus albidus to sclareolide.

General Description

Sclareolide is a diterpenoid compound mainly used in the perfume industry for its amber like odor.

Flammability and Explosibility

Notclassified

InChI:InChI=1/C16H26O2/c1-14(2)7-5-8-15(3)11(14)6-9-16(4)12(15)10-13(17)18-16/h11-12H,5-10H2,1-4H3/t11-,12+,15-,16+/m0/s1

Upstream product

• 13456-36-5 (1R,2R,4aS,8aS)-(2-hydroxy-2,5,5,8a-tetramethylperhydronaphthyl)acetic acid 
• 473-03-0 Ambrein 
• 64681-71-6 14,15-bisnor-8α,12S-epoxylabdan-13-one 
• 1616-86-0 cis-abienol 
• 515-03-7 sclareol 
• 39850-84-5 Acetic acid 1-[2-((1R,2R,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyl-decahydro-naphthalen-1-yl)-ethyl]-1-methyl-allyl ester 
• 103476-92-2 (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan-2-ol 
• 145511-21-3 2-((3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan-2-yl)propan-2-ol 
• 6790-58-5 (-)-ambroxide 
• 64-17-5 ethanol 
• 7664-93-9 sulfuric acid 
• 67-66-3 chloroform 
• 10028-15-6 ozone 
• 105014-29-7 8α-hydroxy-13,14,15,16-tetranorlabdan-12-al 

Downstream Products

• 38419-75-9 (1R,2R,4aS,8aS)-1-(2-hydroxyethyl)-2,5,5,8a-tetramethyl-decahydronaphthalen-2-ol 
• 10207-83-7 (+/-)-(1α,2β,4aβ,8aα)-decahydro-2-hydroxyl-2,5,5,8a-tetramethyl-1-naphthaleneethanol 
• 10207-83-7 rac-13,14,15,16-tetranor-9βH-labdane-8,12-diol 
• 10207-83-7 (+/-)-13,14,15,16-Tetranor-5β-labdane-8β,12-diol 
• 10207-83-7 (+/-)-13,14,15,16-Tetranor-5β,9β-labdane-8β,12-diol 
• 564-20-5 (+/-)-5β,8α-Sclareolide 
• 3738-00-9 (±)-ambrox 
• 564-20-5 norisoambreinolide 
• 3738-00-9 (3aRS,5aSR,9aSR,9bSR)-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan 
• 103476-92-2 (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan-2-ol 
• 6790-58-5 (-)-ambroxide 
• 1788090-69-6 C₂₀H₃₀O₃ 
• 160598-92-5 5S,9S,10S-(-)-(E)-labda-8⁽¹⁷⁾,11,13-trien-16,15-olide 
• 216011-55-1 (5S,9S,10S)-15,16-epoxy-12-hydroxy-labda-8⁽¹⁷⁾-13⁽¹⁶⁾,14-triene 

Relevant articles and documents

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