5717-16-8

Basic information

• Product Name: 2-METHYL-4-OXO-4-(4'-METHOXYPHENYL)BUTYRIC ACID
• Synonyms: 2-METHYL-4-OXO-4-(4'-METHOXYPHENYL)BUTYRIC ACID;4-(4-Methoxyphenyl)-2-Methyl-4-oxobutyric acid, 97%
• CAS NO: 5717-16-8
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.24
• Mol File: 5717-16-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-METHYL-4-OXO-4-(4'-METHOXYPHENYL)BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-4-OXO-4-(4'-METHOXYPHENYL)BUTYRIC ACID(5717-16-8)
• EPA Substance Registry System: 2-METHYL-4-OXO-4-(4'-METHOXYPHENYL)BUTYRIC ACID(5717-16-8)

Safety Data

• Hazardous Substances Data: 5717-16-8(Hazardous Substances Data)

Usage

General Description

2-Methyl-4-oxo-4-(4'-methoxyphenyl)butyric acid is a complex organic chemical compound with potential uses in medicinal chemistry. The exact properties of this compound may vary depending upon its specific formulation and molecular structure. It appears to feature both carboxylic acid and ketone functional groups, which could indicate possible reactivity with bases, reducing agents, and other compounds. Its structure also suggests the presence of aromatic compounds, which are often associated with stability and resonance. The methoxyphenyl component implies potential alterations to its polarity, reactivity, and solubility. As with many organic chemicals, it’s crucial to handle this compound with appropriate care, considering potential risks and safety measures. No specific information is available on its applications or uses, which could be due to the novelty or rarity of the compound in chemical research or industry.

Upstream product

• 100-66-3 methoxybenzene 
• 4100-80-5 2-methylsuccinic anhydride 
• 14308-38-4 2,2-diethoxy-5-(4-methoxy-phenyl)-3-methyl-2,3-dihydro-furan 
• 15118-68-0 ethyl 2-methyl-4-(4-methoxyphenyl)-4-oxobutanoate 
• 15190-13-3 (4-methoxy-phenyl)-morpholin-4-yl-acetonitrile 
• 80-62-6 methacrylic acid methyl ester 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 101973-94-8 3-(4-methoxybenzoyl)-2-methylenepropionic acid 

Downstream Products

• 5750-10-7 4-(4-methoxy-phenyl)-2-methyl-4-oxo-butyric acid methyl ester 
• 196697-06-0 4-(4-methoxyphenyl)-2-methylbutanoic acid 
• 15118-68-0 ethyl 2-methyl-4-(4-methoxyphenyl)-4-oxobutanoate 
• 627877-81-0 carbonic acid 5-(4-methoxyphenyl)-3-methylfuran-2-yl ester phenyl ester 
• 109174-87-0 4-(4-Hydroxy-phenyl)-2-methyl-4-oxo-butyric acid methyl ester 
• 99414-53-6 4-(4-Isopropoxy-phenyl)-2-methyl-4-oxo-butyric acid 
• 15116-30-0 ethyl 4-(4-methoxyphenyl)-2-methylbutanoate 
• 118270-10-3 C₁₁H₁₀N₂O₂ 
• 28657-53-6 6-(p-Methoxyphenyl)-4-methyl-3(2H)-pyridazinone 

Relevant articles and documents

Pd(ii)/Zn co-catalyzed chemo-selective hydrogenation of α-methylene-γ-keto carboxylic acids

An efficient Pd/Zn co-catalyzed chemo-selective hydrogenation of α-methylene-γ-keto carboxylic acids is described. This methodology offers a divergent synthesis of α-methyl-γ-keto carboxylic acids, α-methylcarboxylic acids, and lactones starting from α-me

Enantioselective TADMAP-catalyzed carboxyl migration reactions for the synthesis of stereogenic quaternary carbon

The chiral, nucleophilic catalyst TADMAP [1, 3-(2,2,2-triphenyl-1- acetoxyethyl)-4-(dimethylamino)-pyridine] has been prepared from 3-lithio-4-(dimethylamino)pyridine (5) and triphenylacetaldehyde (3), followed by acylation and resolution. TADMAP catalyzes the carboxyl migration of oxazolyl, furanyl, and benzofuranyl enol carbonates with good to excellent levels of enantioselection. The oxazole reactions are especially efficient and are used to prepare chiral lactams (23) and lactones (30) containing a quaternary asymmetric carbon. TADMAP-catalyzed carboxyl migrations in the indole series are relatively slow and proceed with inconsistent enantioselectivity. Modeling studies (B3LYP/6-31G*) have been used in qualitative correlations of catalyst conformation, reactivity, and enantioselectivity.

Development of Chiral Nucleophilic Pyridine Catalysts: Applications in Asymmetric Quaternary Carbon Synthesis

TADMAP (1a), a new chiral DMAP catalyst, has been designed to place a C(3)-benzylic trityl group over one face of the pyridine ring, while a C(3)-benzylic acetoxy group creates a chirotopic environment on the other face. TADMAP was prepared in four steps