5728-44-9

Basic information

• Product Name: 4-(2-Cyanophenyl)benzoic acid
• Synonyms: 4-(2-Cyanophenyl)benzoic acid;2'-Cyano-4-biphenylcarboxylic acid
• CAS NO: 5728-44-9
• Molecular Formula: C₁₄H₉NO₂
• Molecular Weight: 223.23
• Mol File: 5728-44-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 569.2°C at 760 mmHg
• Flash Point: 298°C
• Appearance: /
• Density: 1.622g/cm³
• Vapor Pressure: 8.55E-14mmHg at 25°C
• Refractive Index: 1.72
• CAS DataBase Reference: 4-(2-Cyanophenyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Cyanophenyl)benzoic acid(5728-44-9)
• EPA Substance Registry System: 4-(2-Cyanophenyl)benzoic acid(5728-44-9)

Safety Data

• Hazardous Substances Data: 5728-44-9(Hazardous Substances Data)

Usage

General Description

4-(2-Cyanophenyl)benzoic acid is a chemical compound with the molecular formula C15H11NO2. It is a derivative of benzoic acid and contains a cyanophenyl group, as indicated by its name. 4-(2-Cyanophenyl)benzoic acid is often used in organic synthesis and medicinal chemistry as a building block for the synthesis of pharmaceutical drugs and other organic compounds. It has potential applications in the development of anti-inflammatory and anti-cancer drugs due to its structural properties and functional groups. Additionally, it has shown potential as a fluorescent probe for the detection of biologically relevant analytes. Overall, 4-(2-Cyanophenyl)benzoic acid is a versatile chemical that has a wide range of potential uses in the field of chemistry and medicine.

InChI:InChI=1/C12H15NO6/c14-8-5-19-11(10(16)9(8)15)13-7-3-1-6(2-4-7)12(17)18/h1-4,8-11,13-16H,5H2,(H,17,18)/t8-,9+,10-,11+/m1/s1

Upstream product

• 89900-98-1 methyl 2'-cyano-[1,1'-biphenyl]-4-carboxylate 
• 3808-94-4 2'-bromobiphenyl-4-carboxylic acid 
• 544-92-3 copper(I) cyanide 
• 2042-37-7 o-cyanobromobenzene 
• 14047-29-1 4-carboxyphenylboronic acid 
• 2052-07-5 2-Bromobiphenyl 
• 3808-91-1 4-acetyl-2'-bromobiphenyl 

Downstream Products

• 89900-98-1 methyl 2'-cyano-[1,1'-biphenyl]-4-carboxylate 
• 679407-02-4 2'-cyano-biphenyl-4-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenyl]-amide 

Relevant articles and documents

PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERSAS AS AGONISTS OF G- PROTEIN COUPLED RECEPTOR 43 (GPR43)

The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases.

Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors incorporating substituted biphenyl P4 motifs

Anthranilamides 4 and 5 were designed and synthesized as selective and orally bioavailable factor Xa inhibitors. Structural modifications aimed at lowering their lipophilicity were performed at the central phenyl ring and at the S4 binding biphenyl region by incorporating water solublizing substituents. The resulting compounds (e.g., 7, 8, 14, 30a, and 32b) are highly potent in vitro, and show improved activity in human plasma-based thrombin generation assay.

PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS

Compounds are provided having a piperazine or homopiperazine ring which are useful in the treatment of thrombosis.