583041-67-2

Basic information

• Product Name: Benzoic acid, 3,4,5-tris(phenylmethoxy)-, 1,2-phenylene ester
• CAS NO: 583041-67-2
• Molecular Formula: C62H50O10
• Molecular Weight: 955.073
• Mol File: 583041-67-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3,4,5-tris(phenylmethoxy)-, 1,2-phenylene ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3,4,5-tris(phenylmethoxy)-, 1,2-phenylene ester(583041-67-2)
• EPA Substance Registry System: Benzoic acid, 3,4,5-tris(phenylmethoxy)-, 1,2-phenylene ester(583041-67-2)

Safety Data

• Hazardous Substances Data: 583041-67-2(Hazardous Substances Data)

Upstream product

• 1486-47-1 3,4,5-tris(benzyloxy)benzoyl chloride 
• 120-80-9 benzene-1,2-diol 
• 1486-48-2 3,4,5-tribenzyloxybenzoic acid 
• 149-91-7 3,4,5-trihydroxybenzoic acid 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 70424-94-1 methyl 3,4,5-tris(benzyloxy)benzoate 
• 99-24-1 methyl galloate 

Relevant articles and documents

Synthesis of poly (3,4,5-trihydroxybenzoate ester) dendrimers and their chemiluminescence

Gallic acid (GA) and gallic acid methyl ester (GM), polyphenol chemiluminescence (CL) compounds, produces light in the presence of alkali and hydrogen peroxide. We synthesized first-generation polyphenol dendrimers with GA units in the periphery and measured their CL for developing a polyphenol compound which has a strong CL intensity. The CL intensities of the poly (3,4,5-trihydroxybenzoate ester) dendrimers 4 and 8 in MeOH are approximately 400- and 600-fold stronger than that of GA, respectively.

Mimic catechins to develop selective MMP-2 inhibitors

Abstract: Matrix metalloproteinase 2 (MMP-2) is a well-known anticancer target belonging to the MMP family. Because of the bilateral role of MMPs in cancer, developing highly selective MMP-2 inhibitors is a current challenge. In this paper, we investigated the binding modes of green tea polyphenols epigallocatechin gallate and epicatechin into the active site of the MMP-2 enzyme. The structure-based analysis allowed the optimization of these hits and hence led to a better lead candidate. Moreover, using a pharmacophore model, we screened FooDB compounds and selected food components as potential MMP-2 inhibitors. The search for food-derived compounds that target this enzyme may represent a strategy to identify new lead molecules with improved safety profiles and provide indications about possible functional foods. Graphical abstract: [Figure not available: see fulltext.].

Synthesis of poly(3,4,5-trihydroxybenzoate) dendrimers from polyphenols and their chemiluminescence

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