58371-98-5

Basic information

• Product Name: 3,5-dichloropentan-2-one
• Synonyms: 3,5-dichloropentan-2-one;2-Pentanone, 3,5-dichloro-;3,5-Dichloro-2-pentanone;Einecs 261-227-0
• CAS NO: 58371-98-5
• Molecular Formula: C₅H₈Cl₂O
• Molecular Weight: 155.02242
• EINECS: 261-227-0
• Mol File: 58371-98-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 214.98°C (rough estimate)
• Flash Point: 82.3 °C
• Appearance: /
• Density: 1.2390
• Vapor Pressure: 0.217mmHg at 25°C
• Refractive Index: 1.4632 (estimate)
• CAS DataBase Reference: 3,5-dichloropentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dichloropentan-2-one(58371-98-5)
• EPA Substance Registry System: 3,5-dichloropentan-2-one(58371-98-5)

Safety Data

• Hazardous Substances Data: 58371-98-5(Hazardous Substances Data)

Usage

General Description

3,5-Dichloropentan-2-one is a chemical substance with the molecular formula C5H8Cl2O. This chemical belongs to the category of organochlorine compounds, specifically those containing a ketone group attached to an aliphatic chain. The ketone functional group (carbon-oxygen double bond) in the 2nd position and the chlorine atoms attached at the 3rd and 5th position of the carbon chain distinguish its structure. Typically, this chemical is used in the field of applied chemistry and research as it forms an integral part of various organic synthesis processes. Its physical, chemical, toxicological properties, as well as its handling and storage information may vary, so it needs to be used, stored, and disposed of with utmost care following guidelines. In addition, more detailed study is needed to understand the full extent of its impact on health and the environment.

InChI:InChI=1/C5H8Cl2O/c1-4(8)5(7)2-3-6/h5H,2-3H2,1H3

Upstream product

• 2986-00-7 3-acetyl-3-chlorodihydrofuran-2(3H)-one 
• 13045-13-1 3-chloro-3-acetylpropanol 
• 75-36-5 acetyl chloride 
• 5891-21-4 5-chloro-2-pentanone 
• 75-09-2 dichloromethane 
• 78-94-4 methyl vinyl ketone 
• 141-97-9 ethyl acetoacetate 
• 107-06-2 1,2-dichloro-ethane 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 54527-68-3 2-chloroethyl acetoacetate 

Downstream Products

• 7275-24-3 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-chloro-ethyl)-4-methyl-thiazolium; chloride-hydrochloride 
• 13051-49-5 5-Acetoxy-3-chloropentan-2-one 
• 5891-21-4 5-chloro-2-pentanone 
• 765-43-5 Cyclopropyl methyl ketone 
• 533-45-9 chlormethiazole 
• 5706-49-0 2-<1-Hydroxy-aethyl>-thiacyclobutan 
• 14066-76-3 4-methyl-5-(β-acetoxyethyl)-2-thiazolinethione 
• 63141-09-3 1-chlorocyclopropyl methyl ketone 
• 31299-91-9 2-chloro-5-(2-chloro-ethyl)-4-methyl-thiazole 
• 120983-72-4 1-chlorocyclopropyl-2-chloro-ethan-1-one 

Relevant articles and documents

Synthesis method of 3,5-dihalogenated-2-pentanone

The invention discloses a synthetic method of 3,5-dihalogenated-2-pentanone, and belongs to the technical field of organic chemistry. According to the method, acetoacetate is taken as a raw material,and cyclopropanation, ring-opening halogenation and hydrolysis decarboxylation reactions are carried out successively so as to obtain 3,5-dihalogenated-2-pentanone. The method has the advantages of simple and accessible raw materials, high atom utilization ratio in the halogenation step and fewer wastes. The reaction conditions of all steps are simple, purification is not needed in the process, continuous feeding can be achieved, cyclic application of the cyclopropanation catalyst can be achieved, and potential industrial amplification prospects are achieved.

A process for preparing 3, 5 - dichloro -2 - pentanone continuous flow method (by machine translation)

The invention relates to a process for preparing 3, 5 - dichloro - 2 - pentanone continuous-flow method, in continuous flow reaction device, through the metering of the reservoir tanks will be α - acetyl - α - chloro - γ - butyrolactone and hydrochloric acid is pumped into the reaction in the device, in the 50 - 90 °C under continuous reaction to obtain 3, 5 - dichloro - 2 - pentanone. The technical scheme of the present invention with compared with traditional kettle reaction method, avoiding the product and acid long-term contact, product with short residence time, does not produce by-products and tar, with operation and after treatment is simple, the product yield and advantage of having high purity. (by machine translation)

Synthetic method of midbody 3,5-dichloro-2-pentanone

The invention discloses a synthetic method of midoby 3,5-dichloro-2-pentanone. The synthetic method adopts alpha-acetyl-gamma-butyrolactone, anhydrous potassium carbonate, alpha-acetyl-alpha-chloro-gamma-butyrolactone, hydrochloric acid, glacial acetic acid, Cu2O, benzidine and anhydrous THF as main raw materials, adopts alpha-acetyl-gamma-butyrolactone to be converted to the corresponding enol structure under the catalytic effect of the lewis acid-sulfonyl chloride, the chloride ions attach the alpha site of carbonyl, then protons are transferred, hydrogen protons are removed from a hydrogengroup, and then the hydrogen protons are re-arranged and converted to the carbonyl with more stable structure. When the acetic acid is used as a solvent and has certain solubility for an organic phaseand the hydrochloric acid, the reaction is easier, the reaction yield is greatly increased under the effect of a catalyst, the production process of prothioconazole is shortened, and the energy consumption is reduced.