5855-52-7

Basic information

• Product Name: 1-Phenyl-5-aminotetrazole
• Synonyms: 2-Phenylquinoline-4-amine;4-Amino-2-phenylquinoline;2-Phenyl-4-aminoquinoline;2-Phenyl-4-quinolinamine;4-Quinolinamine, 2-phenyl-;Aids002822;Aids-002822;Quinoline, 4-amino-2-phenyl-
• CAS NO: 5855-52-7
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.27
• Mol File: 5855-52-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 446.7°Cat760mmHg
• Flash Point: 254.4°C
• Appearance: /
• Density: 1.194g/cm³
• Vapor Pressure: 3.56E-08mmHg at 25°C
• Refractive Index: 1.697
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Phenyl-5-aminotetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-5-aminotetrazole(5855-52-7)
• EPA Substance Registry System: 1-Phenyl-5-aminotetrazole(5855-52-7)

Safety Data

• Hazardous Substances Data: 5855-52-7(Hazardous Substances Data)

Usage

General Description

1-Phenyl-5-aminotetrazole is a chemical compound known for its applications in the field of pyrotechnics and explosives due to its high energy properties. It’s part of the Tetrazole family, substances known for their energetic materials. The chemical is characterized by its formula C7H7N5. Because of its explosive nature, handling and storage of 1-Phenyl-5-aminotetrazole require careful measures. There isn’t much information available about its environmental or health impacts, highlighting the need for caution when dealing with this compound.

InChI:InChI=1/C15H12N2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H2,16,17)

Upstream product

• 612-96-4 2-Phenylquinoline 
• 1144-20-3 2-phenyl-4-quinolinol 
• 29197-45-3 2-phenyl quinoline-4-carboxamide 
• 2786-07-4 2-thienyl lithium 
• 122664-00-0 (E)-2-((1-phenylethylidene)amino)benzonitrile 
• 14442-25-2 3-(2-nitrophenyl)-5-phenyl-1,2-oxazole 
• 4546-48-9 methyl 2-phenylquinoline-4-carboxylate 
• 917-54-4 methyllithium 
• 155057-20-8 4-nitro-2-phenylquinoline 
• 189877-75-6 4-(1,1,1,3,3,3-Hexamethyl-disilazan-2-yl)-2-phenyl-quinoline 
• 7664-41-7 ammonia 
• 4979-79-7 4-chloro-2-phenylquinoline 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 125743-39-7 2-<(benzylidene)amino>benzonitrile 

Downstream Products

• 876499-34-2 N-(2-phenyl-[4]quinolyl)-glycine 
• 1154-49-0 N-(2-phenyl-quinolin-4-yl)-acetamide 
• 101869-07-2 N-(2-phenyl-[4]quinolyl)-acetoacetamide 
• 111272-58-3 4-oxo-5-phenyl-1,4-dihydro-benzo[h][1,6]naphthyridine-3-carboxylic acid ethyl ester 
• 103644-58-2 [(2-phenyl-[4]quinolylamino)-methylene]-malonic acid diethyl ester 
• 105106-34-1 N-(2-phenyl-[4]quinolyl)-2-[(2-phenyl-[4]quinolylamino)-methylene]-malonamic acid ethyl ester 
• 4979-79-7 4-chloro-2-phenylquinoline 
• 5427-93-0 4-bromo-2-phenylquinoline 

Relevant articles and documents

An Improved Environmentally Friendly Approach to 4-Nitro-, 4-Sulfonyl-, and 4-Aminoquinolines and 4-Quinolones through Conjugate Addition of Nucleophiles to β-(2-Aminophenyl)-α,β-ynones

Sequential addition/annulation reactions of sulfinate and nitrite anions to β-(2-aminophenyl)-α,β-ynones led to valuable 4-sulfonylquinolines and 4-nitroquinolines. The latter proved to be versatile precursors of N-unsubstituted 4-aminoquinolines and 4-quinolones. Reaction of β-(2-aminophenyl)-α,β-ynones with DMF/NaOH resulted in the formation of 4-(dimethylamino)quinolines. The use of an alternative CO-free procedure for the preparation of substrates β-(2-aminophenyl)-α,β-ynones allowed extension of the methodology to the synthesis of 4-substituted 2-alkylquinolines.

Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C?O and C?C Bond Activation

An efficient nickel-catalyzed decarbonylative amination reaction of aryl and heteroaryl esters has been achieved for the first time. The new amination protocol allows the direct interconversion of esters and amides into the corresponding amines and represents a good alternative to classical rearrangements as well as cross coupling reactions.

Heterocycle-heterocycle strategies: (2-nitrophenyl)isoxazole precursors to 4-aminoquinolines, 1 H-indoles, and quinolin-4(1 H)-ones

Reductive heterocycle-heterocycle (heterocycle → heterocycle; H-H) transformations that give 4-aminoquinolines, 3-acylindoles, and quinolin-4(1H)-ones from 2-nitrophenyl substituted isoxazoles are reported. When this methodology is applied to 3,5-, 4,5-,