5867-71-0

Basic information

• Product Name: 3-hydroxy-5,6,7,4'-tetramethoxymethoxyflavone
• Synonyms: 3-hydroxy-5,6,7,4'-tetramethoxymethoxyflavone
• CAS NO: 5867-71-0
• Molecular Weight: 358.348
• Mol File: 5867-71-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-5,6,7,4'-tetramethoxymethoxyflavone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-5,6,7,4'-tetramethoxymethoxyflavone(5867-71-0)
• EPA Substance Registry System: 3-hydroxy-5,6,7,4'-tetramethoxymethoxyflavone(5867-71-0)

Safety Data

• Hazardous Substances Data: 5867-71-0(Hazardous Substances Data)

Upstream product

• 2569-77-9 5,6,7,4'-tetra methoxyl-flavanone 
• 41929-26-4 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-3-(4-methoxyphenyl)propenone 
• 1168-42-9 5,6,7,4'-tetramethoxyflavone 
• 17742-46-0 acetic acid 3,4,5-trimethoxy-phenyl ester 
• 22248-14-2 6-hydroxy-2,3,4-trimethoxyacetophenone 
• 642-71-7 3,4,5-trimethoxyphenol 

Downstream Products

• 4324-55-4 3,4',5,6,7-pentahydroxyflavone 
• 4472-73-5 3,5,6,7,4'-pentamethoxyflavone 

Relevant articles and documents

Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase

Baicalein (1), 6-hydroxyapigenin (6), 6-hydroxygalangin (13) and 6-hydroxykaempferol (14), which are naturally occurring flavonoids from a set of 14 hydroxyflavones tested, exhibited high inhibitory effects on tyrosinase with respect to L-DOPA, while each of the 5,6,7-trihydroxyflavones 1, 6, 13 or 14 acted as a cofactor to monophenolase. Moreover, 6-hydroxykaempferol (14) showed the highest activity and was a competitive inhibitor of tyrosinase compared to L-DOPA. 5,6,7-Trihydroxyflavones 1, 6, 13 or 14 showed also high antioxidant activities. Hence, we conclude that the 5,6,7-trihydroxy-flavones are useful as good depigmentation agents with inhibitory effects in addition to their antioxidant properties.