5932-28-5

Basic information

• Product Name: Methyl 4-phenyl-1H-pyrazole-3-carboxylate
• Synonyms: Methyl 4-phenyl-1H-pyrazole-3-carboxylate;VVOAFSOUPLXGJG-UHFFFAOYSA-N
• CAS NO: 5932-28-5
• Molecular Formula: C₁₁H₁₀N₂O₂
• Molecular Weight: 202.2093
• Mol File: 5932-28-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 187 °C
• Boiling Point: 539.2°Cat760mmHg
• Flash Point: 279.9°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 1.08E-11mmHg at 25°C
• Refractive Index: 1.614
• PKA: 10.98±0.50(Predicted)
• CAS DataBase Reference: Methyl 4-phenyl-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-phenyl-1H-pyrazole-3-carboxylate(5932-28-5)
• EPA Substance Registry System: Methyl 4-phenyl-1H-pyrazole-3-carboxylate(5932-28-5)

Safety Data

• Hazardous Substances Data: 5932-28-5(Hazardous Substances Data)

Usage

General Description

Methyl 4-phenyl-1H-pyrazole-3-carboxylate is a chemical compound with the molecular formula C12H11N3O2. It is a white to light yellow solid that is commonly used in the field of organic chemistry as a reagent for the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. This chemical is known for its diverse range of applications, including its use as a building block in the synthesis of biologically active molecules. It is also used as an intermediate in the preparation of pyrazole derivatives, which have been studied for their potential therapeutic applications, such as antitumor, antimicrobial, and anti-inflammatory properties. Additionally, Methyl 4-phenyl-1H-pyrazole-3-carboxylate is known for its role in the development of new materials and chemical processes, making it an important compound in the field of chemical research and development.

InChI:InChI=1/C19H21N3O4/c1-26-18-4-2-3-15(13-18)14-20-9-11-21(12-10-20)19(23)16-5-7-17(8-6-16)22(24)25/h2-8,13H,9-12,14H2,1H3

Upstream product

• 186581-53-3 diazomethane 
• 4891-38-7 phenylpropynoic acid methyl ester 
• 7299-58-3 phenylpropiolyl chloride 
• 67-56-1 methanol 
• 96791-17-2 cis-4-phenyl-3-acetamido-3-carbomethoxy-Δ¹-pyrazoline 
• 96791-18-3 cis-4-phenyl-3-benzamido-3-carbomethoxy-Δ¹-pyrazoline 
• 60676-51-9 methyl (Z)-2-(acetylamino)-3-phenylpropenoate 
• 21462-02-2 methyl (Z)-2-benzoylamino-3-phenyl-2-propenoate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 81190-89-8 methyl 4-bromo-1H-pyrazole-3-carboxylate 
• 98-80-6 phenylboronic acid 

Downstream Products

• 23097-85-0 methyl 2-methyl-4-phenyl-2H-pyrazole-3-carboxylate 
• 7510-56-7 4-phenyl-1H-pyrazole-3-carboxylic acid 
• 96256-54-1 methyl 1-methyl-4-phenyl-1H-pyrazole-3-carboxylate 

Relevant articles and documents

AMINOPYRIMIDINE COMPOUND USED FOR INHIBITING ACTIVITY OF PROTEIN KINASE

The present invention relates to an aminopyrimidine compound having an inhibitory effect on the activity of protein kinase as well as the preparation and use thereof. Specifically, disclosed by the present invention is an aminopyrimidine compound represented by formula (I), or a pharmaceutically acceptable salt, stereoisomer, solvate or hydrate thereof, as well as a pharmaceutical composition comprising said compound and a use method therefor. The method comprises a method for treating cell proliferative diseases and conditions such as cancer and immune diseases.

NEW EFFICIENT SYNTHESIS OF 3(5)-CARBOMETHOXY-4-ARYLPYRAZOLES FROM 3-ARYL-2,3-DEHYDROAMINO ACID DERIVATIVES

3(5)-Carbomethoxy-4-arylpyrazoles can be easily obtained by aromatization with boron trifluoride etherate of 4-aryl-3-acetamido(or benzamido)-3-carbomethoxy-Δ1-pyrazolines synthesized by 1,3-dipolar cycloaddition of diazomethane with 3-aryl-2,3