6059-29-6Relevant articles and documents
Manganese-Based Contrast Agents for Magnetic Resonance Imaging of Liver Tumors: Structure-Activity Relationships and Lead Candidate Evaluation
Wang, Junfeng,Wang, Huan,Ramsay, Ian A.,Erstad, Derek J.,Fuchs, Bryan C.,Tanabe, Kenneth K.,Caravan, Peter,Gale, Eric M.
, p. 8811 - 8824 (2018/10/09)
Gd-based MRI contrast agents (GBCAs) have come under intense regulatory scrutiny due to concerns of Gd retention and delayed toxicity. Three GBCAs comprising acyclic Gd chelates, the class of GBCA most prone to Gd release, are no longer marketed in Europe
AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE
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Paragraph 00341, (2013/06/05)
The present invention relates to the field of medicine. Provided herein are aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in modulating the protein tyrosine kinase activity, and in modulating inter-and/or intra-cellular signaling. Also provided herein are pharmaceutically acceptable compositions comprising the aminoquinazoline compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.
Stereoselective synthesis of swainsonines from pyridines
Heimg?rtner, Gerres,Raatz, Dirk,Reiser, Oliver
, p. 643 - 655 (2007/10/03)
An efficient synthesis of (-)-swainsonine and (-)-2,8a-di-epi-swainsonine was developed starting from readily available 2-pyridinecarbaldehyde and 3-hydroxypyridine. In particular, it was demonstrated that the mixture of simple indolizidines, i.e. lentigi