61886-17-7

Basic information

• Product Name: 1-benzyl-4-phenylpiperidine-4-carboxylic acid
• Synonyms: 1-benzyl-4-phenylpiperidine-4-carboxylic acid;4-Phenyl-1-phenylmethyl-4-piperidinecarboxylic acid;1-benzyl-4-phenylpiperidine-4-carboxylic acid(SALTDATA: 0.6H2O)
• CAS NO: 61886-17-7
• Molecular Formula: C₁₉H₂₁NO₂
• Molecular Weight: 295.37554
• EINECS: 263-282-6
• Mol File: 61886-17-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 454.7°C at 760 mmHg
• Flash Point: 228.8°C
• Appearance: /
• Density: 1.178g/cm³
• Vapor Pressure: 4.66E-09mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: 1-benzyl-4-phenylpiperidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-phenylpiperidine-4-carboxylic acid(61886-17-7)
• EPA Substance Registry System: 1-benzyl-4-phenylpiperidine-4-carboxylic acid(61886-17-7)

Safety Data

• Hazardous Substances Data: 61886-17-7(Hazardous Substances Data)

Usage

General Description

1-benzyl-4-phenylpiperidine-4-carboxylic acid is a chemical compound that belongs to the family of piperidine derivatives. It is a piperidine derivative with a benzyl and phenyl group attached to the piperidine ring, as well as a carboxylic acid group. 1-benzyl-4-phenylpiperidine-4-carboxylic acid has been studied for its potential pharmacological properties, particularly in the field of medicinal chemistry. Its structure suggests that it may have applications in the development of pharmaceuticals, particularly in the areas of neurological disorders and pain management. Further research and studies are needed to fully understand the potential uses and properties of this compound.

InChI:InChI=1/C19H21NO2/c21-18(22)19(17-9-5-2-6-10-17)11-13-20(14-12-19)15-16-7-3-1-4-8-16/h1-10H,11-15H2,(H,21,22)

Upstream product

• 56243-25-5 1-benzyl-4-cyano-4-phenylpiperidine 
• 55-51-6 N,N-bis(2-chloro-ethyl)-benzenemethanamine 
• 101-32-6 N-benzyl-diethanolamine 
• 103-82-2 phenylacetic acid 

Downstream Products

• 84176-76-1 1-benzyl-4-phenyl-piperidine-4-carboxylic acid amide 
• 59084-08-1 1-benzyl-4-phenyl-piperidine-4-carboxylic acid ethyl ester 
• 1013329-92-4 (1-benzyl-4-phenylpiperidin-4-yl)(4-methylpiperazin-1-yl)methanone 
• 77-17-8 Normeperidine 
• 3627-45-0 4-phenyl-piperidine-4-carboxylic acid 

Relevant articles and documents

Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities

A new series of thiazole-substituted 1,1,1,3,3,3-hexafluoro-2-propanols were prepared and evaluated as malonyl-CoA decarboxylase (MCD) inhibitors. Key analogs caused dose-dependent decreases in food intake and body weight in obese mice. Acute treatment with these compounds also led to a drop in elevated blood glucose in a murine model of type II diabetes.

Compounds with analgesic and local anaesthetic effect

New compounds of the formula (A) STR1 a process for their preparation and their use in the manufacture of pharmaceutical preparations. The new compounds have both local anaesthetic and analgesic effect.

1-AZONIABICYCLO[2.2.1]HEPTANES, METHODS OF PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS IN WHICH THEY ARE PRESENT

The invention relates to quaternary basic amides of the formula STR1 in which Ar is an optionally substituted mono-, di-or tricyclic aromatic or heteroaromatic group;T is a direct bond, a hydroxymethylene group, an alkoxymethylene group in which the alkoxy group is C 1-C. sub.4, or a C 1-C 5-alkylene group; Ar' is an unsubstituted or mono-or poly-substituted phenyl, a thienyl, a benzothienyl, a naphthyl or an indolyl; R is hydrogen or a C 1-C. sub.4-alkyl, or a C 1-C 4-ω-alkoxy(C 2-C 4) alkyl, or a C 2-C 4-ω-alkanoyloxy (C 1-C 4)alkyl;.Q is hydrogen;or else Q and R together form a 1,2-ethylene, 1,3-propylene or 1,4-butylene group;Am ⊕ is the radical STR2 in which X 1, X 2 and X 3, together with the nitrogen atom to which they are bonded, form a 1-AZONIABICYCLO[2.2.1] HEPTANE optionally substituted by a phenyl or benzyl group; and A . crclbar. is a pharmaceutically acceptable anion. These compounds are useful for the preparation of drugs intended for the treatment of pathological conditions involving the tachykinin system.