627531-47-9

Basic information

• Product Name: 4-Bromo-3-chloro-2-methylaniline
• Synonyms: 4-Bromo-3-chloro-2-methylaniline 98%;6-Amino-3-bromo-2-chlorotoluene;4-BROMO-3-CHLORO-2-METHYLANILINE, 95+%;4-Bromo-3-chloro-2-methylaniline96%
• CAS NO: 627531-47-9
• Molecular Formula: C₇H₇BrClN
• Molecular Weight: 220.5
• Product Categories: Amines;blocks;Bromides
• Mol File: 627531-47-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 55℃
• Boiling Point: 289.5 °C at 760 mmHg
• Flash Point: 128.9 °C
• Appearance: /
• Density: 1.619 g/cm³
• Vapor Pressure: 0.00219mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.69±0.10(Predicted)
• CAS DataBase Reference: 4-Bromo-3-chloro-2-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-3-chloro-2-methylaniline(627531-47-9)
• EPA Substance Registry System: 4-Bromo-3-chloro-2-methylaniline(627531-47-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 627531-47-9(Hazardous Substances Data)

Usage

General Description

4-Bromo-3-chloro-2-methylaniline is a chemical compound with the molecular formula C7H7BrClN. It is a substituted aniline derivative and is commonly used in organic synthesis and pharmaceutical manufacturing. 4-Bromo-3-chloro-2-methylaniline is a pale yellow solid at room temperature and is slightly soluble in water. It is primarily used as an intermediate in the production of dyes and pharmaceuticals. Additionally, it is known to have potential mutagenic and carcinogenic properties, and proper safety precautions should be taken when handling this substance.

InChI:InChI=1/C7H7BrClN/c1-4-6(10)3-2-5(8)7(4)9/h2-3H,10H2,1H3

Upstream product

• 125328-80-5 N-(4-bromo-3-chloro-2-methylphenyl)acetamide 
• 87-60-5 3-chloro-2-methylbenzenamine 
• 7463-35-6 N-(3-chloro-2-methylphenyl)acetamide 

Downstream Products

• 97329-43-6 1-bromo-2-chloro-3-methyl-benzene 
• 1082041-90-4 5-bromo-4-chloro-1H-indazole 
• 1447125-25-8 C₁₅H₁₅BrClNO₄ 
• 125328-84-9 (5-Bromo-4-chloro-indol-3-yl)-β-L-fucopyranoside 
• 153248-52-3 5-bromo-4-chloro-indol-3-yl-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid) 
• 125328-77-0 N-acetyl-5-bromo-6-chloroanthranilic acid 
• 3030-19-1 2-amino-5-bromo-6-chlorobenzoic acid 
• 125328-80-5 N-(4-bromo-3-chloro-2-methylphenyl)acetamide 
• 6388-45-0 5-bromo-6-chloro-N-[(methoxycarbonyl)methyl]anthranilic acid methyl ester 
• 1607828-63-6 (5-bromo-4-chloroindol-3-yl) (β-D-galactopyranosyl)-(1→4)-β-D-glucopyranoside 
• 7240-90-6 5-bromo-4-chloro-3-indolyl β-D-galactopyranoside 
• 1044256-89-4 1-bromo-3-(bromomethyl)-2-chlorobenzene 

Relevant articles and documents

INHIBITORS OF RENAL OUTER MEDULLARY POTASSIUM CHANNEL

Compounds of Formula I and the pharmaceutically acceptable salts thereof are provided as inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS

The invention provides well-defined aryl fluoroethyl ureas that are useful as selective alpha2 adrenergic agonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with modulation of alpha2 adrenergic receptors.