63365-56-0

Basic information

• Product Name: Ethanone, 2-chloro-1-[4-(phenylmethoxy)phenyl]-
• CAS NO: 63365-56-0
• Molecular Formula: C15H13ClO2
• Molecular Weight: 260.72
• Mol File: 63365-56-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-chloro-1-[4-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-1-[4-(phenylmethoxy)phenyl]-(63365-56-0)
• EPA Substance Registry System: Ethanone, 2-chloro-1-[4-(phenylmethoxy)phenyl]-(63365-56-0)

Safety Data

• Hazardous Substances Data: 63365-56-0(Hazardous Substances Data)

Upstream product

• 54696-05-8 4'-benzyloxy-acetophenone 
• 99-93-4 4-Hydroxyacetophenone 
• 108-95-2 phenol 
• 6305-04-0 p-hydroxyphenacyl chloride 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 4254-67-5 2-bromo-1-(4-benzyloxyphenyl)-1-ethanone 

Downstream Products

• 72734-74-8 (p-benzyloxy-phenyl)-ethyleneoxide 
• 61439-59-6 2-(4-benzyloxyphenyl)ethanol 
• 1252107-47-3 1-(4-(benzyloxy)phenyl)-2-chloroethanol 
• 92850-54-9 2-amino-1-(4-benzyloxy-phenyl)-ethanone 
• 4195-25-9 2-amino-1-(4-benzyloxyphenyl)ethanone hydrochloride 
• 79040-23-6 4-(4-Benzyloxy-phenyl)-thiazol-2-ylamine; hydrochloride 
• 79615-63-7 N-[4-(4-Benzyloxy-phenyl)-thiazol-2-yl]-propionamide 

Relevant articles and documents

Preparation method of 2-(4-benzyloxyphenyl)ethanol

The invention provides a preparation method of 2-(4-benzyloxyphenyl)ethanol. The preparation method comprises the following steps: 1) subjecting phenol to reacting with chloroacetyl chloride under the catalysis of aluminum trichloride to obtain a compound as shown in a formula II; 2) subjecting the compound as shown in the formula II to reacting with benzyl halide under an alkaline condition to obtain a compound as shown in a formula III, wherein the benzyl halide is one selected from benzyl bromide and benzyl chloride; 3) performing reduction treatment on the compound as shown in the formula III, and adjusting a reaction system to be an alkaline system to obtain a compound as shown in a formula IV; and 4) under the action of a catalyst, reducing the compound as shown in the formula IV under a hydrogen condition to obtain the 2-(4-benzyloxyphenyl)ethanol as shown in the formula I. The preparation method has the advantages of low cost, mild reaction conditions, safety in operation and less three-waste pollution, and is beneficial to being applied to industrial production.

Chemoenzymatic synthesis of enantiopure 1-phenyl-2-haloethanols and their esters

Several secondary haloalcohols have been resolved by esterification catalyzed by lipases A and B from Candida antarctica (CALA and CALB, respectively). Immobilized CALB (Novozym 435) gave better selectivities and faster reaction rates than CALA (Novozyme

2-Amino-4-phenylthiazole derivatives as anti-atherogenic agents

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