637031-86-8 Usage
Description
((3,3-difluorocyclobutoxy)Methyl)benzene is a benzene derivative with the molecular formula C12H12F2O, featuring a (3,3-difluorocyclobutoxy)methyl group attached to the benzene ring. This fluorinated benzene compound is utilized in various chemical and pharmaceutical applications due to its unique structure and properties, making it a valuable building block in the synthesis of other organic compounds. The presence of fluorine atoms in the cyclobutoxy group influences the chemical and physical properties of the molecule, which is of significant interest for research and development in organic chemistry.
Uses
Used in Chemical Synthesis:
((3,3-difluorocyclobutoxy)Methyl)benzene is used as a building block in the synthesis of other organic compounds for various applications. Its unique structure and properties make it a versatile component in creating new molecules with specific characteristics.
Used in Pharmaceutical Development:
In the pharmaceutical industry, ((3,3-difluorocyclobutoxy)Methyl)benzene is used as a key intermediate in the development of new drugs. Its incorporation into drug molecules can potentially enhance their efficacy, stability, and other pharmacological properties.
Used in Organic Chemistry Research:
((3,3-difluorocyclobutoxy)Methyl)benzene is utilized as a subject of study in organic chemistry research. The presence of fluorine atoms in the cyclobutoxy group allows for the investigation of how these atoms affect the molecule's reactivity, stability, and other chemical properties, contributing to the advancement of organic chemistry knowledge.
Check Digit Verification of cas no
The CAS Registry Mumber 637031-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,7,0,3 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 637031-86:
(8*6)+(7*3)+(6*7)+(5*0)+(4*3)+(3*1)+(2*8)+(1*6)=148
148 % 10 = 8
So 637031-86-8 is a valid CAS Registry Number.
637031-86-8Relevant articles and documents
Multigram Synthesis of C 4/C5 3,3-Difluorocyclobutyl-Substituted Building Blocks
Melnykov, Kostiantyn P.,Granat, Dmitriy S.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.,Grygorenko, Oleksandr O.
, p. 4949 - 4957 (2018/12/13)
An approach for the multigram synthesis of 3,3-difluorocyclobutyl-substituted building blocks (including carboxylic acid, amines, alcohols, azide, trifluoroborate ketone) is described. It is shown that, in most cases, ethyl 3,3-difluorocyclobutanecarboxylate is a convenient common synthetic intermediate to obtain the target derivatives. For preparation of 3,3-difluorocyclobutanol or -cyclobutanone, an alternative pathway via reaction of dichloroketene and tert -butyl or benzyl vinyl ether should be applied.
