639468-31-8

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 3-(4-fluorobenzoyl)-, 1,1-dimethylethyl ester
• CAS NO: 639468-31-8
• Molecular Formula: C17H22FNO3
• Molecular Weight: 307.365
• Mol File: 639468-31-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 3-(4-fluorobenzoyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 3-(4-fluorobenzoyl)-, 1,1-dimethylethyl ester(639468-31-8)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 3-(4-fluorobenzoyl)-, 1,1-dimethylethyl ester(639468-31-8)

Safety Data

• Hazardous Substances Data: 639468-31-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 149452-46-0 (4-fluorophenyl)piperidin-3-ylmethanone 
• 118156-93-7 3-formylpiperidine-1-carboxylic acid tert-butyl ester 
• 639468-33-0 3-[(4-fluorophenyl)hydroxymethyl]piperidine-1-carboxylic acid tert-butyl ester 
• 352-13-6 4-flourophenylmagnesium bromide 
• 189442-78-2 (±)-tert-butyl 3-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 639468-28-3 3-(4-fluorobenzoyl)piperidine-1-carboxylic acid ethyl ester 
• 769907-38-2 1-benzyl-piperidine-3-carbonyl chloride 
• 71962-74-8 Ethyl nipecotate 
• 72551-53-2 ethyl 1-benzylpiperidine-3-carboxylate 
• 141943-04-6 1-benzylpiperidine-3-carboxylic acid 

Downstream Products

• 645379-37-9 1,1-dimethylethyl-3-fluoro-3-[(4-fluorophenyl)carbonyl]-1-piperidinecarboxylate 
• 645379-83-5 1,1-dimethylethyl-3-[(1E)-3-(ethyloxy)-1-(4-fluorophenyl)-3-oxo-1-propen-1-yl]-1-piperidinecarboxylate 
• 639468-33-0 3-[(4-fluorophenyl)hydroxymethyl]piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS

The disclosure relates to compounds of formula I which are useful as kinase modulators including RIPK1 modulation. The disclosure also provides methods of making and using the compounds for example in treatments related to necrosis or inflammation as well as other indications.

N-BENZYL-3-PHENYL-3-HETEROCYCLYL-PROPIONAMIDE COMPOUNDS AS TACHYKININ AND/ OR SEROTONIN REUPTAKE INHIBITORS

The present invention relates to heterocyclic derivatives of formula (1) wherein R1 represents a 5 or 6 membered heteroaryl group, in which the 5-membered heteroaryl group contains at least one heteroatom selected from oxygen, sulphur or nitrogen and the 6-membered heteroaryl group contains from 1 to 3 nitrogen atoms, or R1 represents a 4,5 or 6 membered heterocyclic group, wherein saids 5 or 6 membered heteroaryl or the 4,5 or 6 membered heterocyclic group may optionally be substituted by one to three substituents, which may be the same or different, selected from (CH2)pR6, wherein p is zero or an integer from 1 to 4 and wherein R and R2- R6 are each as defined in the description and pharmaceutically acceptable salts and solvates thereof; process for their preparation and their use in the treatment of conditions mediated by tachykinins and/or by selective inhibition of serotonin reuptake transporter protein.