769907-38-2 Usage
Description
(4-NITRO-PHENYL)-ACETYL CHLORIDE, with the molecular formula C8H6ClNO3, is an acyl chloride, a type of organic compound that is widely used in chemical reactions to introduce an acyl group into a molecule. This specific compound features a nitro group and an acetyl group, which contribute to its utility in the synthesis of pharmaceuticals and agrochemicals. Additionally, it serves as an intermediate in organic synthesis and can act as a precursor to other functionalized compounds. Due to its toxic and potentially hazardous nature, it should be handled with care.
Uses
Used in Pharmaceutical Industry:
(4-NITRO-PHENYL)-ACETYL CHLORIDE is used as a synthetic intermediate for the development of various pharmaceuticals, leveraging its ability to introduce acyl groups into target molecules, which is crucial for the creation of new drug candidates.
Used in Agrochemical Industry:
In the agrochemical sector, (4-NITRO-PHENYL)-ACETYL CHLORIDE is utilized as a key component in the synthesis of agrochemicals, contributing to the production of effective pest control agents and other agricultural products.
Used in Organic Synthesis:
(4-NITRO-PHENYL)-ACETYL CHLORIDE is employed as a versatile intermediate in organic synthesis, enabling the formation of a range of functionalized compounds for various applications across different industries.
Used as a Precursor Compound:
This acyl chloride also serves as a precursor to other functionalized compounds, playing a significant role in the advancement of chemical research and the development of novel materials and substances.
Check Digit Verification of cas no
The CAS Registry Mumber 769907-38-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,9,9,0 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 769907-38:
(8*7)+(7*6)+(6*9)+(5*9)+(4*0)+(3*7)+(2*3)+(1*8)=232
232 % 10 = 2
So 769907-38-2 is a valid CAS Registry Number.
769907-38-2Relevant articles and documents
Syntheses and Binding Studies of New [(Aryl)(aryloxy)methyl]piperidine Derivatives and Related Compounds as Potential Antidepressant Drugs with High Affinity for Serotonin (5-HT) and Norepinephrine (NE) Transporters
Orjales, Aurelio,Mosquera, Ramón,Toledo, Antonio,Pumar, M. Carmen,García, Neftalí,Cortizo, Lourdes,Labeaga, Luis,Innerárity, Ana
, p. 5512 - 5532 (2007/10/03)
In a wide search program toward new, efficient, and fast-acting antidepressant drugs, we have prepared series of new compounds having an (aryl)(aryloxy)methyl moiety linked directly or through a methylene chain to different substituted and unsubstituted cycles (isoquinoline, piperazine, piperidine, tetrahydropyran, or cyclopentane). These compounds have been evaluated for their affinities for serotonin (5-HT) transporter (SERT) and 5-HT1A and 5-HT2A receptors. Racemic mixtures of 4-[(aryl)(aryloxy)methyl]piperidine derivatives showed much higher affinity values for SERT than fluoxetine and resulted in lack of affinity for 5-HT 1A and 5-HT2A receptors. Some of these racemic mixtures were resolved to their enantiomers and tested for binding to norepinephrine (NE) transporter (NET), dopamine (DA) transporter (DAT), and α2 receptor. Several of these enantiomers [(-)-15b, (-)-15j, (-)-15t, (+)-15u] displayed a dual binding profile with affinities for SERT and NET with K i i = 1.9 and 13.5 nM, respectively), and further pharmacological characterization is in progress for its evaluation as a antidepressant.
