64634-46-4

Basic information

• Product Name: Benzene, 1,1'-[(4-fluorophenyl)methylene]bis[4-methoxy-
• CAS NO: 64634-46-4
• Molecular Formula: C21H19FO2
• Molecular Weight: 322.379
• Mol File: 64634-46-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-[(4-fluorophenyl)methylene]bis[4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-[(4-fluorophenyl)methylene]bis[4-methoxy-(64634-46-4)
• EPA Substance Registry System: Benzene, 1,1'-[(4-fluorophenyl)methylene]bis[4-methoxy-(64634-46-4)

Safety Data

• Hazardous Substances Data: 64634-46-4(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 100-66-3 methoxybenzene 
• 64002-52-4 (4-fluorophenyl)methylene diacetate 

Relevant articles and documents

Transition-Metal-Free Synthesis of Polyfunctional Triarylmethanes and 1,1-Diarylalkanes by Sequential Cross-Coupling of Benzal Diacetates with Organozinc Reagents

A variety of functionalized triarylmethane and 1,1-diarylalkane derivatives were prepared via a transition-metal-free, one-pot and two-step procedure, involving the reaction of various benzal diacetates with organozinc reagents. A sequential cross-coupling is enabled by changing the solvent from THF to toluene, and a two-step SN1-type mechanism was proposed and evidenced by experimental studies. The synthetic utility of the method is further demonstrated by the synthesis of several biologically relevant molecules, such as an anti-tuberculosis agent, an anti-breast cancer agent, a precursor of a sphingosine-1-phosphate (S1P) receptor modulator, and a FLAP inhibitor.