64634-52-2

Basic information

• Product Name: Benzene, 1,1',1''-methylidynetris[4-fluoro-
• CAS NO: 64634-52-2
• Molecular Formula: C19H13F3
• Molecular Weight: 298.307
• Mol File: 64634-52-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1',1''-methylidynetris[4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1',1''-methylidynetris[4-fluoro-(64634-52-2)
• EPA Substance Registry System: Benzene, 1,1',1''-methylidynetris[4-fluoro-(64634-52-2)

Safety Data

• Hazardous Substances Data: 64634-52-2(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 64002-52-4 (4-fluorophenyl)methylene diacetate 
• 379-57-7 4,4',4''-trifluorotriphenylmethanol 

Relevant articles and documents

Transition-Metal-Free Synthesis of Polyfunctional Triarylmethanes and 1,1-Diarylalkanes by Sequential Cross-Coupling of Benzal Diacetates with Organozinc Reagents

A variety of functionalized triarylmethane and 1,1-diarylalkane derivatives were prepared via a transition-metal-free, one-pot and two-step procedure, involving the reaction of various benzal diacetates with organozinc reagents. A sequential cross-coupling is enabled by changing the solvent from THF to toluene, and a two-step SN1-type mechanism was proposed and evidenced by experimental studies. The synthetic utility of the method is further demonstrated by the synthesis of several biologically relevant molecules, such as an anti-tuberculosis agent, an anti-breast cancer agent, a precursor of a sphingosine-1-phosphate (S1P) receptor modulator, and a FLAP inhibitor.

The Reduction of Fluorine-containing Triarylmethanols by Formic Acid

Triarylmethanols containing one or more fluorine substituents in the para-positions are converted by 90 percent formic acid into a mixture of the fluorine-containing triarylmethane, and a second component in which one fluorine has been replaced by a hydro