6772-61-8

Basic information

• Product Name: 1(2H)-Isoquinolinone, 3,4-dihydro-2-(phenylmethyl)-
• CAS NO: 6772-61-8
• Molecular Formula: C16H15NO
• Molecular Weight: 237.301
• Mol File: 6772-61-8.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 1(2H)-Isoquinolinone, 3,4-dihydro-2-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Isoquinolinone, 3,4-dihydro-2-(phenylmethyl)-(6772-61-8)
• EPA Substance Registry System: 1(2H)-Isoquinolinone, 3,4-dihydro-2-(phenylmethyl)-(6772-61-8)

Safety Data

• Hazardous Substances Data: 6772-61-8(Hazardous Substances Data)

Usage

General Description

1(2H)-Isoquinolinone, 3,4-dihydro-2-(phenylmethyl)- is a chemical compound with the molecular formula C17H15NO. It is also known as N-Methyl-N-(phenylmethyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide. It is a derivative of isoquinolinone, and its structure includes a phenylmethyl group attached to the 2-position of the isoquinolinone ring. 1(2H)-Isoquinolinone, 3,4-dihydro-2-(phenylmethyl)- has potential pharmaceutical applications, particularly in the development of new drugs for the treatment of various conditions. It may also be used as a building block for the synthesis of other chemical compounds with similar structural characteristics. However, it is important to handle this compound with care and to adhere to all necessary safety precautions, as it may pose hazards if not used properly.

Upstream product

• 119-67-5 o-carboxybenzaldehyde 
• 67-66-3 chloroform 
• 3647-71-0 N-benzyl-2-phenylethylamine 
• 27326-43-8 2-vinylbenzoic acid 
• 100-46-9 benzylamine 
• 13605-95-3 N-benzyl-1,2,3,4-tetrahydroisoquinoline 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 100-39-0 benzyl bromide 
• 104-63-2 N-Benzylethanolamine 
• 1074-42-6 1-benzylaziridine 
• 299928-52-2 4-bromo-N-quinolin-8-ylbenzamide 
• 33757-54-9 4-chloro-N-(quinolin-8-yl)benzamide 
• 33757-48-1 N-quinolin-8-yl-benzamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 789429-17-0 N-benzyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 126114-98-5 2-benzyl-1-methyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 37039-47-7 2-benzyl-1-cyano-1,2,3,4-tetrahydroisoquinoline bromide 
• 82342-55-0 N-benzoyl-homophthalimide 
• 21640-35-7 N-benzylisoquinoline-1,3,4(2H)-trione 

Relevant articles and documents

Visible-Light-Induced Controlled Oxidation of N-Substituted 1,2,3,4-Tetrahydroisoquinolines for the Synthesis of 3,4-Dihydroisoquinolin-1(2H)-ones and Isoquinolin-1(2H)-ones

A visible light-rose bengal-TBHP mediated, controlled oxidation of N-substituted 1,2,3,4-tetrahydroisoquinolines is developed for the synthesis of 3,4-dihydroisoquinolin-1(2H)-ones and isoquinolin-1(2H)-ones. The present method feature's a broad substrate scope, good functional group tolerances, and the products were prepared in good to excellent yields. The developed methodology further demonstrated in the synthesis of isoindolo[2,1-b] isoquinolin-5(7H)-one (topoisomerase-I inhibitor). (Figure presented.).

Co(iii)-catalysed regioselective linear C(8)-H olefination of isoquinolone with terminal aromatic and aliphatic alkynes

A regioselective C8 linear olefination of isoquinoline-1H-2-one with terminal (aromatic and aliphatic) alkynes is reported under Co(iii) catalysis. This is an exclusive report on the C8 functionalization of isoquinolone using non-noble transition metal co

Oxidation of the inert sp3C-H bonds of tetrahydroisoquinolines through C-H activation relay (CHAR): construction of functionalized isoquinolin-1-ones

A TBN/O2-initiated oxidation of the relatively inert 3,4-C-H bonds of THIQs was accomplished, in which the existence of an α-phosphoric ester group is crucial to enable dioxygen trapping and intramolecular HAT (C-H activation relay,CHAR), reali