6873-59-2

Basic information

• Product Name: N-(4-methylphenylsulfinyl)-N,N-diethylamine
• CAS NO: 6873-59-2
• Molecular Weight: 211.328
• Mol File: 6873-59-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: N-(4-methylphenylsulfinyl)-N,N-diethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methylphenylsulfinyl)-N,N-diethylamine(6873-59-2)
• EPA Substance Registry System: N-(4-methylphenylsulfinyl)-N,N-diethylamine(6873-59-2)

Safety Data

• Hazardous Substances Data: 6873-59-2(Hazardous Substances Data)

Upstream product

• 6873-55-8 p-tolylsulfinyl amide 
• 109-89-7 diethylamine 
• 61582-64-7 N,N-diethyl-O-benzoylhydroxylamine 
• 38078-09-0 diethylamino-sulfur trifluoride 
• 5720-05-8 4-methylphenylboronic acid 
• 195062-57-8 p-tolylboronic pinacol ester 
• 103-19-5 di(p-tolyl) disulfide 
• 106-45-6 para-thiocresol 
• 24398-14-9 1-[(diethylamino)sulfanyl]-4-methylbenzol 
• 98-59-9 p-toluenesulfonyl chloride 
• 10439-23-3 4-methylbenzenesulfinyl chloride 
• 91378-37-9 S,S-diphenyl-(N-p-tolylfulfinyl)sulfoximine 
• 672-78-6 methyl p-toluene sulfinate 

Downstream Products

• 649-15-0 N,N-diethyl-4-methylbenzenesulfonamide 
• 70003-95-1 isopropyl (R)-4-methylbenzenesulfinate 
• 59203-03-1 (R)-isopropyl p-toluenesulfinate 
• 422509-92-0 4-Methyl-benzenesulfinic acid (S)-propyl ester 
• 112458-71-6 ethyl (R)-4-methylbenzenesulfinate 
• 59203-02-0 (R)-ethyl p-toluenesulfinate 
• 64396-66-3 methyl (R)-4-methylbenzenesulfinate 
• 59203-01-9 (S)-(+)-1-methyl 4-methylbenzenesulfinate 

Relevant articles and documents

Rare-Earth-Catalyzed Transsulfinamidation of Sulfinamides with Amines

A rare-earth-catalyzed transsulfinamidation of primary sulfinamides with alkyl, aryl, and heterocyclic amines for the synthesis of diverse secondary and tertiary sulfinamides has been realized. Unlike transition metal-catalyzed cross-coupling approaches restricted to non-commercially available disubstituted O-benzoyl hydroxylamines, this newly developed protocol is suitable for diverse readily available primary and secondary amines without any modifications. Excellent catalytic activity and selectivity are achieved with Eu(OTf)3 under mild reaction conditions, which extends the applicability of rare-earth catalysis.

Copper-Catalyzed Transsulfinamidation of Sulfinamides as a Key Step in the Preparation of Sulfonamides and Sulfonimidamides

Secondary or tertiary sulfinamides are prepared by copper-catalyzed transsulfinamidation of primary sulfinamides with O-benzoyl hydroxylamines. Subsequent oxidations of the resulting products lead to the corresponding sulfonamides. Treatment of N-aryl sulfinamides with O-benzoyl hydroxylamines under copper catalysis provides N-aryl sulfonimidamides.

Metal-Free Cross-Coupling of Arylboronic Acids and Derivatives with DAST-Type Reagents for Direct Access to Diverse Aromatic Sulfinamides and Sulfonamides

We have developed a simple and convenient method for the cross-coupling of arylboronic acids and their derivatives with DAST-type reagents under mild and metal-free conditions to directly afford sulfinamides in moderate to good yields. Moreover, sulfonamides were obtained after a simple oxidation reaction. The reaction mechanism was investigated by18O-labeling experiments, and the synthetic utility was demonstrated by the sulfoxidation of natural products.