690661-10-0

Basic information

• Product Name: heptanoic acid (2-benzoyl-phenyl)-amide
• Synonyms: heptanoic acid (2-benzoyl-phenyl)-amide
• CAS NO: 690661-10-0
• Molecular Weight: 309.408
• Mol File: 690661-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: heptanoic acid (2-benzoyl-phenyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: heptanoic acid (2-benzoyl-phenyl)-amide(690661-10-0)
• EPA Substance Registry System: heptanoic acid (2-benzoyl-phenyl)-amide(690661-10-0)

Safety Data

• Hazardous Substances Data: 690661-10-0(Hazardous Substances Data)

Upstream product

• 549500-24-5 N-(2-benzoylphenyl)propionamide 
• 2528-61-2 Heptanoic acid chloride 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 

Downstream Products

• 88795-69-1 1-Ethyl-3-methyl-4-phenyl-1H-quinolin-2-one 
• 549500-24-5 N-(2-benzoylphenyl)propionamide 
• 37118-75-5 3-methyl-4-(phenyl)-2-(1H)-quinolinone 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 

Relevant articles and documents

Facile synthesis of 4-phenylquinolin-2(1H)-one derivatives from N-acyl-o-aminobenzophenones

An efficient synthesis of 4-phenylquinolin-2(1H)-one derivatives has been achieved in a one-pot reaction from N-acyl-o-aminobenzophenones 1a-c (a: acyl=acetyl; b: acyl=propanoyl; c: acyl=heptanoyl) using NaH as a base. Treatment of 1 with NaH provided the quinolones 2a-c with 62-83% yields, whereas the reaction in the presence of alkyl iodide (alkyl=methyl, ethyl, n-octyl) gave the corresponding N-alkylated quinolones 3a-g in 75-95% yields. The alkylation reaction of 4-phenylquinolin-2(1H)-one 2a with alkyl halide gave a mixture of N-alkylated and O-alkylated products. Comparison of IR and NMR data of the N-alkylated and O-alkylated compounds with those of 2a-c indicated that 2a-c exist as the lactam form.