69380-64-9

Basic information

• Product Name: rac-2,2-dimethyl-4-(3'-hydroxypropyl)-1,3-dioxolan toluene-p-sulphonate
• CAS NO: 69380-64-9
• Molecular Weight: 314.403
• Mol File: 69380-64-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: rac-2,2-dimethyl-4-(3'-hydroxypropyl)-1,3-dioxolan toluene-p-sulphonate(CAS DataBase Reference)
• NIST Chemistry Reference: rac-2,2-dimethyl-4-(3'-hydroxypropyl)-1,3-dioxolan toluene-p-sulphonate(69380-64-9)
• EPA Substance Registry System: rac-2,2-dimethyl-4-(3'-hydroxypropyl)-1,3-dioxolan toluene-p-sulphonate(69380-64-9)

Safety Data

• Hazardous Substances Data: 69380-64-9(Hazardous Substances Data)

Upstream product

• 5470-86-0 1,2,5-triacetoxypentane 
• 14697-46-2 1,2,5-pentanetriol 
• 6318-30-5 2,2-dimethyl-4-(3-hydroxypropyl)-1,3-dioxolane 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 104121-24-6 (+/-)-2-amino-6-benzyloxy-9-[3-(2,2-dimethyl-1,3-dioxolan-4-yl)propyl]purine 
• 177411-59-5 5-Benzylsulfanyl-pentane-1,2-diol 
• 197365-59-6 1-(pent-4-en-1-yl)-1H-pyrrole 
• 106681-49-6 5-N-pyrrolylpentane-1,2-diol 1-p-toluenesulfonate 
• 177411-58-4 4-(3-Benzylsulfanyl-propyl)-2,2-dimethyl-[1,3]dioxolane 

Relevant articles and documents

A synthesis of (-)-tashiromine and formal synthesis of (+)-tashiromine utilizing a highly enantioselective pyrrole/cobaloxime π-cation cyclization

Cyclization of (5-N-pyrrolyl-2-hydroxypentyl)cobaloxime (13) proceeds by intramolecular electrophilic aromatic substitution of a cobaloxime π-cation onto the pyrrole ring to provide 6-exo cyclization product (14) in 95% yield. This cyclization is highly enantioselective. It is applied to a synthesis of highly enantioenriched (-)-tashiromine, (-)-21, and a formal synthesis of (+)-tashiromine.

Antiviral compounds

4-(Guanin-9-yl)butanals and their 3-oxa, 3-thia, and 2-ene counterparts and derivatives thereof, wherein the aldehyde is protected, which have antiviral activity, and are useful in treating viral infections, particularly herpes viral infections, such as h