701294-90-8

Basic information

• Product Name: dimethyl 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]benzylmalonate
• Synonyms: dimethyl 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]benzylmalonate
• CAS NO: 701294-90-8
• Molecular Weight: 468.59
• Mol File: 701294-90-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]benzylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]benzylmalonate(701294-90-8)
• EPA Substance Registry System: dimethyl 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]benzylmalonate(701294-90-8)

Safety Data

• Hazardous Substances Data: 701294-90-8(Hazardous Substances Data)

Upstream product

• 701294-89-5 dimethyl 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]benzylidenemalonate 
• 22824-31-3 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ol 
• 52191-15-8 4-(2-bromoethyloxy)benzaldehyde 
• 701294-88-4 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]benzaldehyde 

Downstream Products

• 701294-91-9 2-(methoxycarbonyl)-3-[4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]phenyl]propionic acid 
• 701294-93-1 methyl 2-carbamoyl-3-[4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtoxy)ethoxy]phenyl]propionate 

Relevant articles and documents

NONCYCLIC 1,3-DICARBONYL COMPOUNDS AS DUAL PPAR AGONISTS WITH POTENT ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC ACTIVITY

Disclosed are the preparation and pharmaceutical use of novel noncyclic 1,3-dicarbonyl compounds of formula I, wherein ring A, ring B, R', R2, R3, R4, R5, X, Y, Z, Q, Ar and n are as defined in the specification. These compounds, as peroxisome proliferator-activated receptor (PPAR) dual agonists for both RXR/PPARgamma and RXRIPPARalpha heterodimers, are useful in the treatment and/or prevention of type 2 diabetes and associated metabolic syndrome such as hypertension, obesity, insulin resistance, hyperlipidemia, hyperglycemia, hypercholesterolemia, atherosclerosis, coronary artery disease, and other cardiovascular disorders.