701294-93-1Relevant articles and documents
Design, synthesis, and evaluation of a new class of noncyclic 1,3-dicarbonyl compounds as PPARα selective activators
Li, Zhibin,Liao, Chenzhong,Ko, Ben C. B.,Shan, Song,Tong, Edith H. Y.,Yin, Zihui,Pan, Desi,Wong, Vincent K. W.,Shi, Leming,Ning, Zhi-Qiang,Hu, Weiming,Zhou, Jiaju,Chung, Stephen S. M.,Lu, Xian-Ping
, p. 3507 - 3511 (2007/10/03)
Lipid accumulation in nonadipose tissues is increasingly linked to the development of type 2 diabetes in obese individuals. We report here the design, synthesis, and evaluation of a series of novel PPARα selective activators containing 1,3-dicarbonyl moie