709007-52-3Relevant articles and documents
Use of a modified Leimgruber-Batcho reaction to prepare 6-chloro-5-fluoroindole
Bentley, Jon M.,Davidson, James E.,Duncton, Matthew A. J.,Giles, Paul R.,Pratt, Robert M.
, p. 2295 - 2300 (2007/10/03)
An efficient synthesis of the title indole, the heterocyclic core of the standard 5-HT2C receptor agonist Ro 60-0175, via a modified Leimgruber-Batcho indole synthesis is presented. The process can be used to make > 100 g quantities of the targ