7144-49-2Relevant articles and documents
Divergent S- And C-Difluoromethylation of 2-Substituted Benzothiazoles
Wang, Xiu,Ye, Wenchao,Kong, Taige,Wang, Chenlu,Ni, Chuanfa,Hu, Jinbo
supporting information, p. 8554 - 8558 (2021/11/13)
Two unprecedented and complementary synthetic strategies for S- and C-difluoromethylation of 2-substituted benzothiazoles have been developed by taking advantage of the remarkably different reactivity of CF2H- and 2-PySO2CF2- nucleophiles. A variety of structurally diverse difluoromethyl 2-isocyanophenyl sulfides and 2-difluoromethylated benzothiazoles were synthesized with these two new synthetic protocols.
Stereoselective Synthesis of C, C-Glycosides from exo-Glycals Enabled by Iron-Mediated Hydrogen Atom Transfer
Tardieu, Damien,Desnoyers, Marine,Laye, Claire,Hazelard, Damien,Kern, Nicolas,Compain, Philippe
supporting information, p. 7262 - 7267 (2019/10/11)
We describe herein a convenient strategy for the construction of C,C-glycoside building blocks via the intermediacy of tertiary pseudoanomeric radicals. Application of an iron-mediated hydrogen atom transfer/Michael-Giese coupling enables the anomeric quaternization of readily available exo-glycals with good to complete stereocontrol in the pyranose and furanose series. Carefully optimized conditions allow the use of challenging trisubstituted derivatives prone to undergo further elaboration to stable neoglycoconjugates. Preliminary results for direct C-disaccharide synthesis are also discussed.
Kinetic Modelling of the catalytic oxidation of 2-(methylmercapto)-benzothiazole under mild conditions
Córdoba,Saux,Pierella
, p. 173 - 180 (2017/07/27)
2-(Methylmercapto)-benzothiazole oxidation was performed over Copper modified zeolites. The microporous materials were synthesized by the hydrothermal crystallization method and later modified with metal incorporation by wet impregnation. The solid cataly