722486-66-0

Basic information

• Product Name: Acetic acid, (cyclopropylamino)oxo-, ethyl ester (9CI)
• Synonyms: Acetic acid, (cyclopropylamino)oxo-, ethyl ester (9CI);Acetic acid, 2-(cyclopropylamino)-2-oxo-, ethyl ester;ethyl (cyclopropylamino)(oxo)acetate
• CAS NO: 722486-66-0
• Molecular Formula: C₇H₁₁NO₃
• Molecular Weight: 157.16714
• Product Categories: GLYCINESCAFFOLD
• Mol File: 722486-66-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acetic acid, (cyclopropylamino)oxo-, ethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (cyclopropylamino)oxo-, ethyl ester (9CI)(722486-66-0)
• EPA Substance Registry System: Acetic acid, (cyclopropylamino)oxo-, ethyl ester (9CI)(722486-66-0)

Safety Data

• Hazardous Substances Data: 722486-66-0(Hazardous Substances Data)

Upstream product

• 95-92-1 oxalic acid diethyl ester 
• 765-30-0 Cyclopropylamine 
• 4755-77-5 Ethyl oxalyl chloride 

Downstream Products

• 183235-79-2 (cyclopropylamino)(oxo)acetic acid 
• 945255-55-0 C₃₇H₆₀N₆O₇ 
• 35265-06-6 2-(cyclopropylamino)ethan-1-ol 
• 1464139-80-7 5-(6-benzyloxy-3-ethyl-1H-indazol-5-yl)-4-(4-morpholin-4-yl-phenyl)-4H-[1,2,4]triazole carboxylic acid cyclopropylamide 
• 1622209-06-6 N-cyclopropyl-N'-{2-[(3-fluoro-4-methylphenyl)amino]pyridin-3-yl}ethanediamide 
• 1622208-35-8 N-cyclopropyl-3-(3,4-dichlorophenyl)-3H-imidazo[4,5-b]pyridine-2-carboxamide 
• 1622208-11-0 N-cyclopropyl-3-(3-fluoro-4-methylphenyl)-3H-imidazo[4,5-b]pyridine-2-carboxamide 

Relevant articles and documents

Direct C?H Carbamoylation of Nitrogen-Containing Heterocycles

Nucleophilic radical additions at innately electrophilic C(sp2) centers are perfectly suited for the direct functionalization of heterocycles. Using bench stable and commercially available alkyl oxamate and oxamic acid derivatives in combination with photoredox catalysis, a direct carbamoylation of heterocycles yielding amide functionalized pharmacophores in a single step is reported. The reaction conditions reported are compatible with structurally complex heterocyclic substrates of pharmaceutical interest. Notably, derivatives containing functional groups incompatible with standard amidation reactions, such as carboxylic acids and unprotected amines, were found to be amenable to this reaction paradigm.

Substituted heteroaryl compounds and compositions and uses thereof (by machine translation)

The invention discloses substituted heteroaryl compounds and compositions thereof and their use. The compounds of formula (I) compound or type shown in (I) a compound represented by stereo isomers, tautomers, nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt or its prodrug. The invention also provides a pharmaceutical composition, the compounds and pharmaceutical compositions can be regulated protein kinase, particularly Aurora kinase and JAK kinase activity, for the prevention, treatment, treatment and reduce protein kinase, in particular JAK kinase activity mediated diseases or disorders. (by machine translation)

Azabenzimidazole Compounds

The present invention is directed to compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein.