7364-47-8Relevant articles and documents
Asymmetric synthesis of 4(R)tert-butyl-8a(S)hydroxycarbonyl-4,6,7,8,8a,9-hexahydro-1-alkylpyrr olo[3,2-f]indolizines via intramolecular iminium ion cyclization
Annunziata, Rita,Ferrari, Marinella,Papeo, Gianluca,Resmini, Marina,Sisti, Massimo
, p. 23 - 38 (1997)
Enantiomerically pure compounds embodying the 4,6,7,8,8a,9-hexahydropyrrolo[3,2-f]indolizine unit were synthesized via intramolecular iminium ion cyclization. An improved procedure for the preparation of the oxazolidinone 1 is also reported.
Synthesis of mono-and diphosphorus-substituted proline derivatives containing P–C–N fragments
Prishchenko,Livantsov,Novikova,Livantsova,Petrosyan
, p. 1846 - 1854 (2017/03/22)
Convenient methods for the synthesis of new types of mono-and diphosphorus-substituted proline derivatives containing P–C–N fragments were developed based on special pre-prepared proline-containing synthons. The corresponding organophosphorus acids including a proline fragment were also synthesized.
Novel catalysts for the enantioselective Henry reaction
Veselovsky,Stepanov
, p. 422 - 425 (2015/02/02)
Two novel catalytic systems based on the CuII complexes with N-(3,5-dibromo-2-hydroxybenzyl)- and N-(2-hydroxy-3-nitrobenzyl)-(S)-α,α-diphenylprolinols were developed. These systems catalyze the condensation of 4-nitrobenzaldehyde with nitromethane to produce S-nitroaldol with maximum enantiomeric excess of >90% (99% yield). The reactions of nitromethane with aliphatic aldehydes give the corresponding products in the yields above 80% and ee > 90%.
