7465-96-5

Basic information

• Product Name: N-(4-bromophenyl)-4-methoxybenzamide
• Synonyms: N-(4-bromophenyl)-4-methoxybenzamide;UKRORGSYN-BB BBV-075715
• CAS NO: 7465-96-5
• Molecular Formula: C₁₄H₁₂BrNO₂
• Molecular Weight: 306.1546
• Mol File: 7465-96-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 344°Cat760mmHg
• Flash Point: 161.8°C
• Appearance: /
• Density: 1.468g/cm³
• Vapor Pressure: 6.79E-05mmHg at 25°C
• Refractive Index: 1.64
• CAS DataBase Reference: N-(4-bromophenyl)-4-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromophenyl)-4-methoxybenzamide(7465-96-5)
• EPA Substance Registry System: N-(4-bromophenyl)-4-methoxybenzamide(7465-96-5)

Safety Data

• Hazardous Substances Data: 7465-96-5(Hazardous Substances Data)

Usage

General Description

N-(4-bromophenyl)-4-methoxybenzamide is a chemical compound with the formula C14H12BrNO2. It is an amide derivative of 4-methoxybenzoic acid, containing a bromo-substituted phenyl group. N-(4-bromophenyl)-4-methoxybenzamide is commonly used in organic synthesis and medicinal chemistry, serving as a building block for the preparation of various pharmaceuticals and biologically active molecules. It may also exhibit some pharmacological properties, although its specific uses and effects have not been extensively studied. Overall, N-(4-bromophenyl)-4-methoxybenzamide is an important intermediate in chemical and pharmaceutical applications, with potential for further research and development.

InChI:InChI=1/C14H12BrNO2/c1-18-13-8-2-10(3-9-13)14(17)16-12-6-4-11(15)5-7-12/h2-9H,1H3,(H,16,17)

Upstream product

• 58618-94-3 benzoic p-methoxybenzoic anhydride 
• 106-40-1 4-bromo-aniline 
• 100-07-2 4-methoxy-benzoyl chloride 
• 7465-88-5 4-methoxy-N-phenylbenzamide 
• 62-53-3 aniline 
• 3424-93-9 4-methoxyphenylacetamide 
• 589-87-7 1,4-bromoiodobenzene 

Downstream Products

• 127351-04-6 N-(4-Bromo-phenyl)-4-methoxy-thiobenzamide 
• 154558-92-6 6-bromo-2-(4-methoxyphenyl)-1,3-benzothiazole 

Relevant articles and documents

Activated charcoal supported copper nanoparticles: A readily available and inexpensive heterogeneous catalyst for the N-arylation of primary amides and lactams with aryl iodides

A novel heterogeneous copper catalyst has been developed by supporting copper nanoparticles on activated charcoal via in situ reducing copper(II) with aqueous hydrazine as reductant. The characterization of Cu/C catalyst showed that the Cu0 nano-particles were formed on the surface of charcoal. This catalyst displayed good catalytic activities toward the N-arylation of primary amides and lactams with aryl iodides.

Combining Eosin y with Selectfluor: A Regioselective Brominating System for Para-Bromination of Aniline Derivatives

A mild, metal-free, and absolutely para-selective bromination of aniline derivatives has been developed in excellent yields, wherein the organic dye Eosin Y is employed as the bromine source in company with Selectfluor. Neither air nor moisture sensitive, this facile reaction proceeds smoothly at room temperature and completes within a short time. Mechanistic studies indicate a radical pathway; therefore, the existence of an in situ generated brominating reagent, "Selectbrom", is postulated, which may reasonably account for the unique regioselectivity for the para-bromination of N-acyl- as well as N-sulfonylanilines.

Synthesis, anticancer activity and docking of some substituted benzothiazoles as tyrosine kinase inhibitors

Protein tyrosine kinases occupy a central position in the control of cellular proliferation and its inactivation might lead to the discovery of a new generation anticancer compounds. Substituted benzothiazoles have been found to mimic the ATP-competitive