7498-66-0

Basic information

• Product Name: 3,4'-Dichlorobenzophenone
• Synonyms: (3-chlorophenyl)(4-chlorophenyl)methanone(SALTDATA: FREE);(3-chlorophenyl)(4-chlorophenyl)methanone
• CAS NO: 7498-66-0
• Molecular Formula: C₁₃H₈Cl₂O
• Molecular Weight: 251.11
• Mol File: 7498-66-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 375.6°Cat760mmHg
• Flash Point: 158.8°C
• Appearance: /
• Density: 1.311g/cm³
• Vapor Pressure: 7.7E-06mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: 3,4'-Dichlorobenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4'-Dichlorobenzophenone(7498-66-0)
• EPA Substance Registry System: 3,4'-Dichlorobenzophenone(7498-66-0)

Safety Data

• Hazardous Substances Data: 7498-66-0(Hazardous Substances Data)

Usage

General Description

3,4'-Dichlorobenzophenone is a chemical compound with the molecular formula C13H8Cl2O. It is a white crystalline solid that is insoluble in water but soluble in organic solvents. 3,4'-Dichlorobenzophenone is used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It has also been used as a photoinitiator in the production of photopolymer materials. 3,4'-Dichlorobenzophenone is classified as a hazardous substance and should be handled with caution due to its potential health and environmental risks.

InChI:InChI=1/C13H8Cl2O/c14-11-6-4-9(5-7-11)13(16)10-2-1-3-12(15)8-10/h1-8H

Upstream product

• 109406-95-3 1-(3-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethylene 
• 766-84-7 3-chloro-benzonitrile 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 122-01-0 4-chloro-benzoyl chloride 
• 108-90-7 chlorobenzene 
• 133031-93-3 C₃₅H₂₈Cl₂N₃O₃P 
• 618-46-2 m-Chlorobenzoyl chloride 
• 106-39-8 bromochlorobenzene 
• 587-04-2 m-Chlorobenzaldehyde 
• 837-58-1 2-amino-4'-chloro-5-chlorobenzophenone 
• 133069-24-6 C₁₇H₁₃Cl₃N₂O₃ 
• 133031-82-0 C₁₇H₁₃Cl₂N₅O₃ 
• 108-37-2 1-bromo-3-chlorobenzene 
• 75748-10-6 trimethyl-4-chlorobenzoylsilane 

Downstream Products

• 93765-30-1 (3-Chloro-phenyl)-(4-chloro-phenyl)-pyrimidin-5-yl-methanol 
• 812684-98-3 2-(3-chloro-phenyl)-2-(4-chloro-phenyl)-[1,3]dioxolane 
• 13421-95-9 3,4'-dichlorobenzhydrol 
• 13389-45-2 3,4'-dichlorobenzhydryl chloride 
• 54979-73-6 N-(p-chlorophenyl)-m-chlorobenzamide 

Relevant articles and documents

NEW CYCLOADDUCT PRECURSORS OF DIHALOBENZOPHENONES AND PREPARATIONS THEREOF

The invention relates to new compounds of formula (I): wherein X represents a halogen atom selected from the group consisting of fluorine, chlorine, bromine and iodine, which are useful for the preparation of 4,4' dihalobenzophenones of formula (III): wherein X is as defined above.

Pd-Catalyzed Suzuki–Miyaura Cross-Coupling of Arylboronic Acids and α-Iminonitriles through C–CN Bond Activation

A Pd-catalyzed Suzuki–Miyaura cross-coupling reaction between arylboronic acids and α-iminonitriles has been developed. The reaction proceeds through selective activation of the C–CN bond, tolerates a wide range of substituents, and delivers the versatile ketone products in moderate to excellent yields.

Tetraethylammonium iodide catalyzed synthesis of diaryl ketones via the merger of cleavage of C-C double bonds and recombination of aromatic groups

An efficient method for synthesizing diaryl ketones via merging of oxidative cleavage of C-C double bonds and recombination of aromatic groups is developed with Et4NI (2.5 mol%) as the catalyst and NaIO4 as the oxidant. The control experiments provide valuable mechanistic insights into the formation of diaryl ketones, and suggest that NaIO4 serves as an epoxidation and nucleophilic deformylation reagent.